The abundance of tumour‐infiltrating T‐cells has been associated with microsatellite
instability (MSI) and a favourable prognosis in colorectal cancer. However, numerous …

Immune cells in the tumor microenvironment have an important role in regulating tumor
progression. Therefore, stimulating immune reactions to tumors can be an attractive …

To understand the genetic drivers of immune recognition and evasion in colorectal cancer,
we analyzed 1,211 colorectal cancer primary tumor samples, including 179 classified as …

Objective Accumulating evidence links the intestinal microbiota and colorectal
carcinogenesis. Fusobacterium nucleatum may promote colorectal tumour growth and …

Importance Evidence indicates a complex link between gut microbiome, immunity, and
intestinal tumorigenesis. To target the microbiota and immunity for colorectal cancer …

Background Regular use of aspirin after a diagnosis of colon cancer has been associated
with a superior clinical outcome. Experimental evidence suggests that inhibition of …

Background & Aims Evidence supports a carcinogenic role of Escherichia coli carrying the
pks island that encodes enzymes for colibactin biosynthesis. We hypothesized that the …

OBJECTIVES: Evidence suggests a possible role ofFusobacterium nucleatumin colorectal
carcinogenesis, especially in right-sided proximal colorectum. Considering a change in …

Objective Colorectal cancer is typically classified into proximal colon, distal colon and rectal
cancer. Tumour genetic and epigenetic features differ by tumour location. Considering a …

BRAF mutation in colorectal cancer is associated with microsatellite instability (MSI) through
its relationship with high-level CpG island methylator phenotype (CIMP) and MLH1 promoter …