Recent advancements in the multicomponent synthesis of heterocycles integrated with a pyrano [2, 3-d] pyrimidine core
Heterocyclic compounds incorporated with a pyranopyrimidine skeleton have received
substantial consideration owing to their privileged, and intelligible biodiversity. Accordingly …
substantial consideration owing to their privileged, and intelligible biodiversity. Accordingly …
Importance of Hybrid Catalysts toward the Synthesis of 5H-Pyrano[2,3-d]pyrimidine-2-ones/2,4-diones (Thiones)
The pyranopyrimidine core is a key precursor for medicinal and pharmaceutical industries
due to its broader synthetic applications as well as its bioavailability. Among its four possible …
due to its broader synthetic applications as well as its bioavailability. Among its four possible …
Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs
Heterocycles containing the pyranopyrimidine motif have attracted the interest of
researchers in recent decades due to their ability to synthesize and explore at a large scale …
researchers in recent decades due to their ability to synthesize and explore at a large scale …
[HTML][HTML] A Review on Barbituric Acid and Its Derivatives: Synthesis, Reactions, and Bio-Applications
Barbituric acid is a heterocyclic compound with various pharmacological and biological
applications. This review paper provides a comprehensive overview of barbituric acid's …
applications. This review paper provides a comprehensive overview of barbituric acid's …
The liquid phase of 4, 4'-trimethylenedipiperidine: a safe and greener dual-task agent for clean and facile synthesis of coumarin derivatives
H Gorjian, NG Khaligh - Molecular Diversity, 2022 - Springer
A practical and facile synthesis of various coumarin derivatives was conducted using a liquid
phase of 4, 4'-trimethylenedipiperidine as a safe and greener dual-task reagent under …
phase of 4, 4'-trimethylenedipiperidine as a safe and greener dual-task reagent under …
Impact of a homogeneous hydrogen bond catalysis for the ethyl (hetero) arylidene cyanoacetate preparation in the presence of TMDP
The synthesis of ethyl (hetero) arylidene cyanoacetates, valuable intermediates in organic
chemistry, has been investigated using several commercially available and synthetic …
chemistry, has been investigated using several commercially available and synthetic …
Determining the pKa1 and pKa2 Values of 4,4′-Trimethylenedipiperidine (TMDP), a Diprotic Organic Base with Unknown pKa Values
L Zaharani, NG Khaligh - Journal of Solution Chemistry, 2024 - Springer
The negative logarithm of the acid dissociation constant values (p K a1 and p K a2) of 4, 4′-
trimethylenedipiperidine (TMDP) was determined by a pH metric titration at 298 K. The …
trimethylenedipiperidine (TMDP) was determined by a pH metric titration at 298 K. The …
Student exploration of the Henderson-Hasselbach equation and pH readings to determine the pK a value of 4,4′-trimethylenedipiperidine (TMDP)
L Zaharani, NG Khaligh - Chemistry Teacher International, 2023 - degruyter.com
This educatory experiment uses an inexpensive pH meter to determine an approximate
negative logarithm of the acid dissociation constant (p K a) value of 4, 4 …
negative logarithm of the acid dissociation constant (p K a) value of 4, 4 …
4,4′-Trimethylenedipiperidine, a safe and greener alternative for piperidine, catalyzed the synthesis of N-methyl imines
H Gorjian, NG Khaligh - Research on Chemical Intermediates, 2022 - Springer
A practical and facile synthesis of various N-methyl imines, versatile scaffolds, was
conducted at 85° C using 4, 4′-trimethylenedipiperidine as a safe and green catalyst. This …
conducted at 85° C using 4, 4′-trimethylenedipiperidine as a safe and green catalyst. This …
Simultaneous activation of aldehydes and methylamine liberation by 4,4ʹ-trimethylenedipiperidine in the solid-state synthesis of N-methyl imines
L Zaharani, M Ghafarikhaligh, S Titinchi… - Research on Chemical …, 2023 - Springer
Abstract The commercially available 4, 4ʹ-trimethylenedipiperidine (TMDP) was used in the
solid state to activate various aldehydes and controlled the libration of methyl amine for …
solid state to activate various aldehydes and controlled the libration of methyl amine for …