Multifunctional exosome-mimetics for targeted anti-glioblastoma therapy by manipulating protein corona

JY Wu, YJ Li, J Wang, XB Hu, S Huang, S Luo… - Journal of …, 2021 - Springer
Targeted drug delivery to the glioblastoma (GBM) overcoming blood–brain barrier (BBB) has
been challenging. Exosomes are promising vehicles for brain tumor drug delivery, but the …

Cyclic RGD conjugated PEG-PLGA nanoparticle enhances preventative effect of bilirubin on the development of ultraviolet-B (UVB)-induced cataract

H Jin, Y Huang, Y Jin, L Wang, F Xiao, F Qian… - Chemical Engineering …, 2024 - Elsevier
Age related cataract (ARC) is characterized by protein conformational disorder with aging
stands out as an independent risk factor. Therefore, mitigation of oxidative stress and DNA …

CPP Functionalized Nanoparticles

Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
In this chapter, the delivery of biomolecules such as oligonucleotides, proteins, peptides and
others by connection of the power of modern nanoparticles with the flexibility and efficacy of …

Precise engineering of Cisplatin prodrug into supramolecular nanoparticles: Enhanced on in vitro antiproliferative activity and treatment and care of in vivo renal injury

Z Zhou, X Chen - Process Biochemistry, 2021 - Elsevier
Renal cell carcinoma (RCC) is a widespread type of urological tumor that derives from the
highly heterogeneous epithelium of the kidney tissue. For the past decade, the treatment of …

An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family

C Cegarra, B Cameron, C Chaves, T Dabdoubi, TM Do… - Plos one, 2022 - journals.plos.org
Background Increasing brain exposure of biotherapeutics is key to success in central
nervous system disease drug discovery. Accessing the brain parenchyma is especially …

Découverte de nouveaux récepteurs capables de médier la transcytose à travers la barrière hémato-encéphalique

C Cegarra - 2022 - theses.hal.science
La barrière hémato-encéphalique est extrêmement sélective pour protéger le cerveau des
xénobiotiques présents dans la circulation systémique. Ces propriétés physiologiques sont …