Understanding the neurotrophic virus mechanisms and their potential effect on systemic lupus erythematosus development

FR Uribe, VPI González, AM Kalergis, JA Soto… - Brain Sciences, 2024 - mdpi.com
Central nervous system (CNS) pathologies are a public health concern, with viral infections
one of their principal causes. These viruses are known as neurotropic pathogens …

Antiviral immunity within neural stem cells distinguishes Enterovirus-D68 strain differences in forebrain organoids

C Vazquez, SG Negatu, CD Bannerman… - Journal of …, 2024 - Springer
Neural stem cells have intact innate immune responses that protect them from virus infection
and cell death. Yet, viruses can antagonize such responses to establish neuropathogenesis …

[HTML][HTML] Bithiazole inhibitors of PI4KB show broad-spectrum antiviral activity against different viral families

MG Martina, V Carlen, S Van der Reysen, E Bianchi… - Antiviral Research, 2024 - Elsevier
Broad-spectrum antivirals can be extremely important for pandemic preparedness. Targeting
host factors dispensable for the host but indispensable for the virus can result in high barrier …

Antiviral immunity within neural stem cells distinguishes viral strain differences in forebrain organoids

C Vazquez, SG Negatu, CD Bannerman, S Sriram… - bioRxiv, 2024 - biorxiv.org
Neural stem cells have intact innate immune responses that protect them from virus infection
and cell death. Yet, viruses can antagonize such responses to establish neuropathogenesis …