Over the course of the aging process, fibroblasts lose contractility, leading to reduced
connective-tissue stiffness. A promising therapeutic avenue for functional rejuvenation of …

Abstract Viral protein 9 (VP9) is a non‐structural protein of white spot syndrome virus
(WSSV) highly expressed during the early stage of infection. The crystal structure of VP9 …

In this book chapter, we summarize the current findings for the physical and chemical
connections between the extracellular matrix (ECM) and 3D chromosome organization …

In the eukaryotic nucleus, DNA, packaged in the form of chromatin, is subject to continuous
damage. Chromatin has to be remodeled in order to repair such damage efficiently. But …

This doctoral thesis explores the remarkable domain of mechanobiology, transcriptional
regulation, and its relevance in regenerative medicine. Cells are known to be plastic …

In this article, we summarize current findings for the emergence of biophysical properties
such as nuclear stiffness, chromatin compaction, chromosome positioning, and chromosome …

Described herein are nucleic acid molecules and complexes useful as i-switch pH reporters
that have increased sensi tivities as a pH reporter and have alternate pH reporting capacity …

2021-09-13 Assigned to THE UNIVERSITY OF CHICAGO, THE NATIONAL CENTRE FOR
BIOLOGICAL SCIENCES reassignment THE UNIVERSITY OF CHICAGO ASSIGNMENT OF …

In the eukaryotic nucleus, DNA, packaged in the form of chromatin, is subject to continuous
damage. Chromatin has to be remodeled in order to repair such damage efficiently. But …

Fibroblasts, one of the major type of cells in connective tissue, experience compressive
forces (CF) in their local microenvironment. These CFs influence their behaviour by altering …