There has been a significant increase in obesity rates worldwide with the corresponding
surge in diabetes. Diabetes causes various microvascular and macrovascular changes often …

(CVD) in individuals with type 1 diabetes mellitus (T1DM), the pathophysiology underlying
the relationship between cardiovascular events, CVD risk factors, and T1DM is not well …

Stroke is the second leading cause of death with substantial unmet therapeutic needs. To
identify potential stroke therapeutic targets, we estimate the causal effects of 308 plasma …

Over the last several decades, the global incidence and prevalence of diabetes mellitus has
increased significantly. The raised incidence rate is projected to continue as greater …

Background Uncertainties persist about the magnitude of associations of diabetes mellitus
and fasting glucose concentration with risk of coronary heart disease and major stroke …

Ischemic stroke is caused by insufficient cerebrovascular blood and oxygen supply. It is a
major contributor to death or disability worldwide and has become a heavy societal and …

Background The association between type 1 diabetes mellitus (T1DM) and specific
cardiovascular diseases (CVD) is uncertain. Furthermore, data on type 2 diabetes mellitus …

Diabetes and ischaemic stroke often arise together. People with diabetes have more than
double the risk of ischaemic stroke after correction for other risk factors, relative to …

Prevention of Cardiovascular Disease in Type 1 Diabetes | New England Journal of Medicine
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For years, it has been recognized that the incidence of coronary heart disease (CHD) in
women lags behind that of men by≈ 10 years, 7 thus generating hypotheses that …