Dementia is a complex set of disorders affecting normal cognitive function. Recently, several
clinical studies have shown that diabetes, obesity, and components of the metabolic …

Extracellular vesicles are secreted by a wide variety of cells, and their primary functions
include intercellular communication, immune responses, human reproduction, and synaptic …

Alzheimer's disease (AD) is a progressive, late-onset dementia with no effective treatment
available. Recent studies suggest that AD pathology is driven by age-related changes in …

Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

The abnormal accumulation of amyloid-β (Aβ) in the central nervous system is a hallmark of
Alzheimer's disease (AD). The regulation of the processing of the single-transmembrane …

Aging is by far the most prominent risk factor for Alzheimer's disease (AD), and both aging
and AD are associated with apparent metabolic alterations. As developing effective …

Obesity, prediabetes, and diabetes are growing in prevalence worldwide. These metabolic
disorders are associated with neurodegenerative diseases, particularly Alzheimer's disease …

Icariin, a major prenylated flavonoid found in Epimedium spp., is a bioactive constituent of
Herba Epimedii and has been shown to exert neuroprotective effects in experimental …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by amyloid-β (Aβ)
plaques and the formation of neurofibrillary tangles (NFTs) composed of …

Somatic disturbances that occur in parallel with psychiatric diseases are a major challenge
in clinical practice. Various factors contribute to the development of mental and somatic …