The transplantation (implantation) of xenograft heart valves into humans has been carried
out for> 50 years. There has been considerable research into making this form of …

Serious tick-induced allergies comprise mammalian meat allergy following tick bites and tick
anaphylaxis. Mammalian meat allergy is an emergent allergy, increasingly prevalent in tick …

Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

Bioprosthetic heart valves (BHVs) are commonly used to replace severely diseased heart
valves but their susceptibility to structural valve degeneration (SVD) limits their use in young …

Instability of the dentine-resin interface is owed to the partial/incomplete penetration of the
resin adhesives in the collagen fibrils. However, interfacial hydrolysis of the resin-matrix …

Abstract Purpose of Review The alpha-Gal (α-Gal) syndrome is characterized by the
presence of IgE antibodies directed at the carbohydrate galactose-alpha-1, 3-galactose (α …

Coronary artery bypass grafting (CABG) remains the most common procedure used in
cardiovascular surgery for the treatment of severe coronary atherosclerotic heart disease. In …

Bioprosthetic heart valves (BHVs) originating from pigs are extensively used for heart valve
replacement in clinics. However, recipient immune responses associated with chronic …

Glutaraldehyde‐fixed bioprosthetic heart valves (GBHV s), derived from pigs or cows,
undergo structural valve deterioration (SVD) over time, with calcification and eventual …

Abstract The α-Gal epitope (Galα1, 3Galα1, 4GlcNAc‑R) is ubiquitously presented in non-
primate mammals, marsupials and New World Monkeys, but it is absent in humans, apes …