Risk factors for amyotrophic lateral sclerosis

C Ingre, PM Roos, F Piehl, F Kamel… - Clinical epidemiology, 2015 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. It is typically
fatal within 2–5 years of symptom onset. The incidence of ALS is largely uniform across most …

ALS: A bucket of genes, environment, metabolism and unknown ingredients

M Zufiria, FJ Gil-Bea, R Fernandez-Torron… - Progress in …, 2016 - Elsevier
The scientific scenario of amyotrophic lateral sclerosis (ALS) has dramatically changed
since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal …

Pathogenesis of amyotrophic lateral sclerosis

S Morgan, RW Orrell - British medical bulletin, 2016 - discovery.ucl.ac.uk
INTRODUCTION: Amyotrophic lateral sclerosis (ALS) or motor neuron disease is a rapidly
progressive neurodegenerative disorder. The primary involvement is of motor neurons in the …

Epidemiology of amyotrophic lateral sclerosis: a review of literature

P Couratier, P Corcia, G Lautrette, M Nicol, PM Preux… - Revue …, 2016 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of motor
neurons, resulting in worsening weakness of voluntary muscles until death occurs from …

[HTML][HTML] Amyotrophic lateral sclerosis and environmental factors

V Bozzoni, O Pansarasa, L Diamanti, G Nosari… - Functional …, 2016 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that affects central
and peripheral motor neuron cells. Its etiology is unknown, although a relationship between …

Strictly monitored exercise programs reduce motor deterioration in ALS: preliminary results of a randomized controlled trial

C Lunetta, A Lizio, VA Sansone, NM Cellotto… - Journal of …, 2016 - Springer
The objective of our study was to perform a randomized controlled trial (RCT) aimed to
evaluate the effects of three strictly monitored exercise programs (SMEP) compared to …

[HTML][HTML] Effects of exercise on sleep in neurodegenerative disease

AA Memon, JJ Coleman, AW Amara - Neurobiology of disease, 2020 - Elsevier
As the population ages, the incidence and prevalence of neurodegenerative disorders will
continue to increase. Persons with neurodegenerative disease frequently experience sleep …

Amyotrophic lateral sclerosis

JS Salameh, RH Brown Jr, JD Berry - Seminars in neurology, 2015 - thieme-connect.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily affecting the
upper and lower motor neurons. The lifetime risk of developing ALS is estimated at 1: 350 for …

Genetics and sex in the pathogenesis of amyotrophic lateral sclerosis (ALS): is there a link?

F Trojsi, G D'Alvano, S Bonavita… - International journal of …, 2020 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no known
cure. Approximately 90% of ALS cases are sporadic, although multiple genetic risk factors …

Recent advances in amyotrophic lateral sclerosis

N Riva, F Agosta, C Lunetta, M Filippi, A Quattrini - Journal of neurology, 2016 - Springer
ALS is a relentlessly progressive and fatal disease, with no curative therapies available to
date. Symptomatic and palliative care, provided in a multidisciplinary context, still remains …