Non-alcoholic fatty liver disease (NAFLD) is currently the world's most common liver
disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic …

Non-alcoholic fatty liver disease (NAFLD), currently the leading cause of global chronic liver
disease, has emerged as a major public health problem, more efficient therapeutics of which …

Obesity is characterized by the deposition of excessive body fat, and is caused by energy
imbalance, especially when consuming fat-rich diets. High fat diet (HFD)-associated obesity …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

The pathophysiology of NAFL and NASH is complex and numerous intermediaries are
involved. Each year brings new and exciting developments as pieces of the …

Increased fructose consumption has been suggested to contribute to non-alcoholic fatty liver
disease (NAFLD), dyslipidemia, and insulin resistance, but a causal role of fructose in these …

With the aging of global population, the incidence of nonalcoholic fatty liver disease
(NAFLD) has surged in recent decades. NAFLD is a multifactorial disease that follows a …

Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic
histopathological changes ranging from non-inflammatory intracellular fat deposition to non …

Mitochondrial pyruvate carrier 1 regulates fatty acid syntha... : Hepatology Mitochondrial pyruvate
carrier 1 regulates fatty acid synthase lactylation and mediates treatment of nonalcoholic fatty …

IL11 is important for fibrosis in non-alcoholic steatohepatitis (NASH) but its role beyond the
stroma in liver disease is unclear. Here, we investigate the role of IL11 in hepatocyte …