Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression

E Yang, X Wang, Z Gong, M Yu, H Wu… - Signal transduction and …, 2020 - nature.com
Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …

The key role of exosomes on the pre-metastatic niche formation in tumors

X Yang, Y Zhang, Y Zhang, S Zhang, L Qiu… - Frontiers in molecular …, 2021 - frontiersin.org
Exosomes or other extracellular vesicles released from cells play an important role in cell-to-
cell communication by transferring bio-information (DNA, coding/non-coding RNA, and …

Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p

L Yu, B Sui, W Fan, L Lei, L Zhou… - Journal of …, 2021 - Wiley Online Library
In patients with prostate cancer (PCa), bone lesions appear osteoblastic in radiographs;
however, pathological fractures frequently occur in PCa patients, and bone resorption is …

[HTML][HTML] Tumor-derived Cav-1 promotes pre-metastatic niche formation and lung metastasis in breast cancer

Y Wang, Y Li, J Zhong, M Li, Y Zhou, Q Lin, S Zong… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Rationale: Breast cancer (BC), as one of the most frequently diagnosed cancer, has
a poor prognosis due to the development of distant metastasis. Among the BC metastatic …

Biology of cancer; from cellular and molecular mechanisms to developmental processes and adaptation

IG Motofei - Seminars in Cancer Biology, 2022 - Elsevier
Cancer research has been largely focused on the cellular and molecular levels of
investigation. Recent data show that not only the cell but also the extracellular matrix plays a …

Nanomedicine to target multidrug resistant tumors

E Lepeltier, P Rijo, F Rizzolio, R Popovtzer… - Drug Resistance …, 2020 - Elsevier
Nanomedicine employs nanotechnologies to develop innovative applications, and more
specifically nano-objects in the field of human health, through exploitation of the physical …

Extracellular vesicles and oncogenic signaling

A Schubert, M Boutros - Molecular oncology, 2021 - Wiley Online Library
In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic
markers for cancer therapy. While the field of EV research is rapidly developing and their …

A herringbone mixer based microfluidic device HBEXO-chip for purifying tumor-derived exosomes and establishing miRNA signature in pancreatic cancer

Y Zhang, X Tong, L Yang, R Yin, Y Li, D Zeng… - Sensors and Actuators B …, 2021 - Elsevier
Exosomes, which are lipid membrane-enclosed nanovesicles (30− 150 nm in diameter),
contain abundant proteomic and genetic information. Specifically, tumor-derived exosomes …

[HTML][HTML] Extracellular vesicle-mediated transport: Reprogramming a tumor microenvironment conducive with breast cancer progression and metastasis

D Brena, MB Huang, V Bond - Translational oncology, 2022 - Elsevier
Breast cancer metastatic progression to critical secondary sites is the second leading cause
of cancer-related mortality in women. While existing therapies are highly effective in …

Exosomes based advancements for application in medical aesthetics

B Zhang, J Gong, L He, A Khan, T Xiong… - … in Bioengineering and …, 2022 - frontiersin.org
Beauty is an eternal pursuit of all people. Wound repair, anti-aging, inhibiting
hyperpigmentation and hair loss are the main demands for medical aesthetics. At present …