NMR as a “gold standard” method in drug design and discovery

AH Emwas, K Szczepski, BG Poulson, K Chandra… - Molecules, 2020 - mdpi.com
Studying disease models at the molecular level is vital for drug development in order to
improve treatment and prevent a wide range of human pathologies. Microbial infections are …

Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters

X Wang, O Boudker - Elife, 2020 - elifesciences.org
Glutamate transporters are essential players in glutamatergic neurotransmission in the
brain, where they maintain extracellular glutamate below cytotoxic levels and allow for …