Mitochondria are semi‐autonomous organelles which are endowed with the ability to
change their shape (eg, by elongation, shortening, branching, buckling, swelling) and their …

Peroxisomes are subcellular organelles found in all eukaryotic cells. In the liver they are
usually round and measure about 0.5–1.0 μm; in rodents they contain a prominent …

Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling
(NVC) has an essential role in maintenance of healthy cognitive function. In aging increased …

A stereological method for obtaining estimates of the total number of neurons in five major
subdivisions of the rat hippocampus is described. The new method, the optical fractionator …

Malignant cells often display defects in autophagy, an evolutionarily conserved pathway for
degrading long-lived proteins and cytoplasmic organelles. However, as yet, there is no …

3-Methyladenine (5 mM) inhibits endogenous protein degradation in isolated rat
hepatocytes by about 60%, while having no adverse effect on the degradation of an …

By means of quantitative analysis of the tissue components in the cortex of the mouse, this
book presents an overall picture of the cortical network which is then related to various …

Retinal pigment epithelium (RPE) of 50 human eyes, five from each 10 decades of life, were
analyzed using ultrastructural morphometric techniques. Content of three types of pigments …

When biochemical studies on the liver are interpreted, the cells of the sinusoidal area
frequently receive little attention because, compared to hepatocytes, their contribution to …

The eIF2α kinases are a family of evolutionarily conserved serine/threonine kinases that
regulate stress-induced translational arrest. Here, we demonstrate that the yeast eIF2α …