The presence of microcalcifications in the breast microenvironment, combined with the
growing evidences of the possible presence of osteoblast-like or osteoclast-like cells in the …

The regulation of gene expression through histone posttranslational modifications plays a
crucial role in breast cancer progression. However, the molecular mechanisms underlying …

Ductal carcinoma in situ (DCIS) is considered a non-invasive precursor to breast cancer,
and although associated with an increased risk of developing invasive disease, many …

In mice, the lack of secreted frizzled-related protein 1 (SFRP1) is responsible for
mammogenesis and hyperplasia, while, in bovines, its overexpression is associated with …

Background: Endocrine-disrupting chemicals have been shown to have broad effects on
development, but their mutagenic actions that can lead to cancer have been less clearly …

Simple Summary Breast cancer is a global burden with the most severe subtype being triple
negative breast cancer (TNBC). Despite advances in conventional therapies, treatment for …

Abstract Background Canine mammary tumours (CMTs) are the most frequent tumours in
intact female dogs and show strong similarities with human breast cancer. In contrast to the …

Simple Summary Secreted Frizzled-Related Protein 1 (SFRP1) expression is decreased
during breast cancer progression and inversely associated with breast tissue age-related …

Women with germline PTEN variants (PTEN hamartoma tumor syndrome, PHTS) have up to
85% lifetime risk of female breast cancer (BC). We previously showed that PHTS-derived …

Cancer is a serious health problem, with a rising trend in its occurrence documented
globally. Female breast cancer is the most common type of cancer worldwide with treatment …