International consensus statement on allergy and rhinology: rhinosinusitis 2021
RR Orlandi, TT Kingdom, TL Smith… - International forum of …, 2021 - Wiley Online Library
I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …
Chronic rhinosinusitis pathogenesis
WW Stevens, RJ Lee, RP Schleimer… - Journal of Allergy and …, 2015 - Elsevier
There are a variety of medical conditions associated with chronic sinonasal inflammation,
including chronic rhinosinusitis (CRS) and cystic fibrosis. In particular, CRS can be divided …
including chronic rhinosinusitis (CRS) and cystic fibrosis. In particular, CRS can be divided …
IL‐33: biological properties, functions, and roles in airway disease
LY Drake, H Kita - Immunological reviews, 2017 - Wiley Online Library
Summary Interleukin (IL)‐33 is a key cytokine involved in type 2 immunity and allergic
airway diseases. Abundantly expressed in lung epithelial cells, IL‐33 plays critical roles in …
airway diseases. Abundantly expressed in lung epithelial cells, IL‐33 plays critical roles in …
Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps
Background IL-25 can function as an early signal for the respiratory type 2 response
characteristic of allergic asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). In …
characteristic of allergic asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). In …
Biomarkers in chronic rhinosinusitis with nasal polyps
AD Workman, MA Kohanski… - … and Allergy Clinics, 2018 - immunology.theclinics.com
Chronic rhinosinusitis (CRS) is a prevalent and heterogeneous disease associated with a
high degree of morbidity. Although there exist specific conditions for diagnosis, it has been …
high degree of morbidity. Although there exist specific conditions for diagnosis, it has been …
Pathogenesis of eosinophilic chronic rhinosinusitis
SA Shah, H Ishinaga, K Takeuchi - Journal of inflammation, 2016 - Springer
Eosinophilic chronic rhinosinusitis (ECRS) is considered a refractory and intractable
disease. Patients with ECRS present with thick mucus production, long-term nasal …
disease. Patients with ECRS present with thick mucus production, long-term nasal …
Immune dysregulation in the functional gastrointestinal disorders
Gastrointestinal conditions may be broadly classified into two: organic and functional
disease, with functional disorders accounting for the majority of patients with chronic …
disease, with functional disorders accounting for the majority of patients with chronic …
Insights into group 2 innate lymphoid cells in human airway disease
MR Karta, DH Broide, TA Doherty - Current allergy and asthma reports, 2016 - Springer
Recent discoveries have led to the identification of a novel group of immune cells, the innate
lymphoid cells (ILCs). The members of this group are divided into three subpopulations …
lymphoid cells (ILCs). The members of this group are divided into three subpopulations …
Comparison between signature cytokines of nasal tissues in subtypes of chronic rhinosinusitis
DK Kim, KM Eun, MK Kim, D Cho… - Allergy, asthma & …, 2019 - synapse.koreamed.org
Purpose Endotype in chronic rhinosinusitis (CRS) has been established in the last decade.
However, the exact immunologic profile of CRS still has controversy because it has a …
However, the exact immunologic profile of CRS still has controversy because it has a …
Key role of the epithelium in chronic upper airways diseases
The respiratory epithelium of the upper airways is a first‐line defence against inhaled
irritants, pathogens and allergens. It ensures a physical barrier provided by apical junctions …
irritants, pathogens and allergens. It ensures a physical barrier provided by apical junctions …