Natural products: an evolving role in future drug discovery

BB Mishra, VK Tiwari - European journal of medicinal chemistry, 2011 - Elsevier
The therapeutic areas of infectious diseases and oncology have benefited from abundant
scaffold diversity in natural products, able to interact with many specific targets within the cell …

[PDF][PDF] The story of beta-sitosterol-a review.

S Saeidnia, A Manayi, AR Gohari, M Abdollahi - 2014 - researchgate.net
Aims: Phytosterols are a subgroup of the steroids, as an important class of bioorganic
molecules, widespread in plants, animals, marines as well as fungi and have similarity to …

Current developments of coumarin compounds in medicinal chemistry

XM Peng, G LV Damu, H Zhou - Current pharmaceutical …, 2013 - ingentaconnect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

[HTML][HTML] In-depth pharmacological and nutritional properties of bael (Aegle marmelos): A critical review

T Sarkar, M Salauddin, R Chakraborty - Journal of agriculture and food …, 2020 - Elsevier
Aegle marmelos or bael has been known from prehistoric times in India with mythological
importance. Each part of the tree like root, bark, fruit, leaf, and flower has therapeutic …

Insecticidal and antifungal chemicals produced by plants: a review

I Boulogne, P Petit, H Ozier-Lafontaine… - Environmental chemistry …, 2012 - Springer
Leaf-cutting ants of the Attini tribe are a major pest of agricultural and forestry productions in
the New World. Economic losses caused by these ants were estimated at several million …

Natural product based leads to fight against leishmaniasis

N Singh, BB Mishra, S Bajpai, RK Singh… - Bioorganic & medicinal …, 2014 - Elsevier
The growing incidence of parasitic resistance against generic pentavalent antimonials,
specifically for visceral disease in Indian subcontinent, is a serious issue in Leishmania …

Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells

ST Pan, Y Qin, ZW Zhou, ZX He, X Zhang… - Drug design …, 2015 - Taylor & Francis
Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone; PLB), a naturally occurring
naphthoquinone isolated from the roots of Plumbaginaceae plants, has been reported to …

Phytochemical profile and pharmacological activity of Aegle marmelos Linn.

B Manandhar, KR Paudel, B Sharma, R Karki - Journal of integrative …, 2018 - Elsevier
Abstract Aegle marmelos Linn.(Rutaceae), commonly known as “bael” in Nepal and India, is
a valuable medicinal plant and is considered sacred by the Hindus. It is used to cure several …

Structure-activity-relationship and mechanistic insights for anti-HIV natural products

R Kaur, P Sharma, GK Gupta, F Ntie-Kang, D Kumar - Molecules, 2020 - mdpi.com
Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …

Coumarins from Rutaceae: Chemical diversity and biological activities

CMS Junior, SMC Silva, EM Sales, E da Silva Velozo… - Fitoterapia, 2023 - Elsevier
Rutaceae is a family expressed by approximately 2100 species distributed in 154 genera
widespread in tropical and temperate regions of Australasia, America, and South Africa …