Cardiovascular disease is a leading cause of death worldwide and accounts for> 17.3
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …

Remodeling of large and small arteries contributes to the development and complications of
hypertension. The focus of this review is some of the mechanisms involved in the …

Accumulating evidence supports the importance of redox signaling in the pathogenesis and
progression of hypertension. Redox signaling is implicated in many different physiological …

Royal jelly (RJ) is a natural bee product with great potential for use in medicine. The
chemical composition of RJ indicates the presence of various bioactive substances …

Aims Cystathionine gamma-lyase (CSE)-derived H2S plays an important role in regulating
cell growth. Lack of CSE expression results in development of hypertension. The current …

Significance: The vascular extracellular matrix (ECM) not only provides mechanical stability
but also manipulates vascular cell behaviors, which are crucial for vascular function and …

Evidence is increasing in hypertensive models for an inflammatory reaction in the
microcirculation with abnormal leukocyte counts and adhesion to the endothelium …

Background Death of smooth muscle cells in the atherosclerotic plaques makes the plaques
more prone to rupture, which can initiate an acute ischemic event. The development of …

Royal jelly (RJ), secreted by honeybee workers, plays diverse roles as nutrients and
defense agents for honeybee biology and human health. Despite being reported to be …

Uterine spiral artery remodeling is one of the key maternal adaptations of pregnancy,
allowing delivery of the large volumes of maternal blood required for both placental and fetal …