Biological systems are by nature multiscale, consisting of subsystems that factor into
progressively smaller units in a deeply hierarchical structure. At any level of the hierarchy …

The construction of high-performance microbial cell factories (MCFs) is the centerpiece of
biomanufacturing. However, the complex metabolic regulatory network of microorganisms …

Identifying the evolution path of a research field is essential to scientific and technological
innovation. There have been many attempts to identify the technology evolution path based …

Biomaterial augmentation of surgically repaired rotator cuff tendon tears aims to improve the
high failure rates (∼ 40%) of traditional repairs. Biomaterials that can alter cellular …

At the heart of the cellular machinery through the regulation of cellular functions, protein–
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …

Autophagy plays a crucial role in maintaining cellular homeostasis through the degradation
of unwanted materials like damaged mitochondria and misfolded proteins. However, the …

The ever-increasing demand for energy, along with worldwide policies aiming sustainability,
resulted in an escalation of research projects focusing on alternative routes for energy …

Abstract The Gene Ontology (GO) is a central resource for functional-genomics research.
Scientists rely on the functional annotations in the GO for hypothesis generation and couple …

Network biology has become crucial to understanding the complex structural characteristics
of biological systems. Consequently, advanced visualization approaches are needed to …

Abstract Lipocalin 2 (LCN2) is a member of the lipocalin family. Elevated expression of
LCN2 has been observed in many human tumors, suggesting it might be a potential …