The role of the Eph receptor family in tumorigenesis

M Anderton, E van der Meulen, MJ Blumenthal… - Cancers, 2021 - mdpi.com
Simple Summary The Eph receptor family is implicated in both tumour promotion and
suppression, depending on the tissue-specific context of available receptor interactions with …

Host-targeted interventions as an exciting opportunity to combat malaria

K Vijayan, L Wei, EKK Glennon, C Mattocks… - Chemical …, 2021 - ACS Publications
Terminal and benign diseases alike in adults, children, pregnant women, and others are
successfully treated by pharmacological inhibitors that target human enzymes. Despite …

Reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) by SARS-CoV-2 in non-hospitalised HIV-infected patients

H Lambarey, MJ Blumenthal, A Chetram… - …, 2024 - thelancet.com
Summary Background While acute SARS-CoV-2 infection and associated inflammation
resulted in substantial morbidity and mortality during the COVID-19 pandemic, particularly in …

Kaposi's sarcoma-associated herpesvirus, but not epstein-barr virus, Co-infection associates with coronavirus disease 2019 severity and outcome in South African …

MJ Blumenthal, H Lambarey, A Chetram… - Frontiers in …, 2022 - frontiersin.org
In South Africa, the Coronavirus Disease 2019 (COVID-19) pandemic is occurring against
the backdrop of high Human Immunodeficiency Virus (HIV), tuberculosis and non …

Antibodies targeting KSHV gH/gL reveal distinct neutralization mechanisms

T Fricke, AK Großkopf, A Ensser, M Backovic, AS Hahn - Viruses, 2022 - mdpi.com
Kaposi's sarcoma herpesvirus (KSHV) is associated with a significant disease burden, in
particular in Sub-Sahara Africa. A KSHV vaccine would be highly desirable, but the …

Cellular receptors involved in KSHV infection

E van der Meulen, M Anderton, MJ Blumenthal… - Viruses, 2021 - mdpi.com
The process of Kaposi's Sarcoma Herpes Virus'(KSHV) entry into target cells is complex and
engages several viral glycoproteins which bind to a large range of host cell surface …

[HTML][HTML] Kaposi's sarcoma-associated herpesvirus at 27

MM Gaglia - Tumour Virus Research, 2021 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV) was discovered 27 years ago and its link
to several pathologies–Kaposi's sarcoma, primary effusion lymphoma, and the B cell variant …

Evidence for altered host genetic factors in KSHV infection and KSHV‐related disease development

MJ Blumenthal, EM Cornejo Castro… - Reviews in medical …, 2021 - Wiley Online Library
Kaposi's sarcoma‐associated herpesvirus (KSHV) is the etiological agent of Kaposi's
sarcoma (KS), the most common AIDS‐related malignancy. It also causes other rare, but …

Kaposi sarcoma‐associated herpesvirus, HIV‐1 and Kaposi sarcoma risk in black South Africans diagnosed with cancer during antiretroviral treatment rollout

M Motlhale, M Muchengeti, D Bradshaw… - … journal of cancer, 2023 - Wiley Online Library
Kaposi sarcoma‐associated herpesvirus (KSHV) causes Kaposi sarcoma (KS). The risk of
KS is amplified in HIV‐immunosuppressed individuals and antiretroviral therapy (ART) …

[HTML][HTML] Potential entry receptors for human γ-herpesvirus into epithelial cells: A plausible therapeutic target for viral infections

A Rani, S Jakhmola, S Karnati, HS Parmar… - Tumour Virus Research, 2021 - Elsevier
Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and
Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in …