Antibiotic resistance is a global human health threat, causing routine treatments of bacterial
infections to become increasingly difficult. The problem is exacerbated by biofilm formation …

Bone biomaterials play a vital role in bone repair by providing the necessary substrate for
cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In …

Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

The rising incidence of bone disorders has resulted in the need for more effective therapies
to meet this demand, exacerbated by an increasing ageing population. Bone tissue …

Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Recent advances in regenerative medicine have confirmed the potential to manufacture
viable and effective tissue engineering 3D constructs comprising living cells for tissue repair …

The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …

In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Surface topography impacts on cell growth and differentiation, but it is not trivial to generate
defined surface structures and to assess the relevance of specific topographic parameters …