Polycyclic aromatic hydrocarbons (PAHs) are often detected in the environment and are
regarded as endocrine disruptors. We here designated mixtures of PAHs in the environment …

The aryl hydrocarbon receptor (AhR) is a transcriptional factor that regulates multiple
functions following its activation by a variety of ligands, including xenobiotics, natural …

Some cytochrome P450 (CYP) heme-thiolate enzymes participate in the detoxication and,
paradoxically, the formation of reactive intermediates of thousands of chemicals that can …

Exposure to toxic polycyclic aromatic hydrocarbons raises a number of toxic and
carcinogenic responses in experimental animals and humans mediated for the most part by …

The nuclear factor-kappaB (NF-κB) transcription factors have emerged as major regulators
of programmed cell death (PCD) whether via apoptosis or necrosis. In this context, NF-κB's …

CK2 genes are overexpressed in many human cancers, and most often overexpression is
associated with worse prognosis. Site-specific expression in mice leads to cancer …

Aryl hydrocarbon receptor (AHR), a cytosolic ligand-activated transcription factor, belongs to
the member of bHLH/PAS family of heterodimeric transcriptional regulators and is widely …

Background Naringenin, a flavonoid compound, has a wide variety of uses in the
pharmaceutical industry for its antioxidant and anti-inflammatory potential. Objectives The …

Cancer is a leading cause of death worldwide. Cancer cells proliferate uncontrollably and,
many cases, spread to other parts of the body. A protein historically involved in cancer is …

CK2 is a highly conserved tetrameric serine/threonine kinase present in all eukaryotic
organisms. It is constitutively active, and appears to be regulated by level of expression and …