Drug hypersensitivity reactions (DHRs) are nowadays the third cause of allergy after rhinitis
and asthma with a significant increase in prevalence in both adults and paediatric …

In respect to the major gastrointestinal disorders associated with oral administration of
Lornoxicam, LOR, a potent anti-inflammatory drug, topical delivery could be an alternative …

Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are classified as type
B adverse drug reactions, and are severe, potentially fatal rare disorders. However, the …

Abstract Background Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis
(TEN) not only cause acute, devastating mucocutaneous reactions but also have long …

Background: Evidence for the risk and incidence of anticonvulsant-induced Stevens-
Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Japan is scarce. Methods …

What is known and objective Despite the numerous studies investigating drug‐induced
Stevens‐Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), the understanding and …

PURPOSE To compare the clinical features and visual outcomes in children and adults with
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). DESIGN …

Purpose: Over the last decade, there has been tremendous progress in the treatment of
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). To understand …

Large health system databases have revolutionized our understanding of the epidemiology
of adverse drug reactions and immunologically mediated drug hypersensitivity. Population …

Severe drug eruption (SDE), a common skin disease, becomes dangerous when it occurs in
patients with human immunodeficiency virus (HIV). However, the molecular mechanisms are …