Function of dental follicle progenitor/stem cells and their potential in regenerative medicine: from mechanisms to applications

R Bi, P Lyu, Y Song, P Li, D Song, C Cui, Y Fan - Biomolecules, 2021 - mdpi.com
Dental follicle progenitor/stem cells (DFPCs) are a group of dental mesenchyme stem cells
that lie in the dental follicle and play a critical role in tooth development and maintaining …

Mechanisms during osteogenic differentiation in human dental follicle cells

C Morsczeck - International Journal of Molecular Sciences, 2022 - mdpi.com
Human dental follicle cells (DFCs) as periodontal progenitor cells are used for studies and
research in regenerative medicine and not only in dentistry. Even if innovative regenerative …

The role of Wnt signaling in postnatal tooth root development

N Tokavanich, MN Wein, JD English, N Ono… - Frontiers in dental …, 2021 - frontiersin.org
Appropriate tooth root formation and tooth eruption are critical for achieving and maintaining
good oral health and quality of life. Tooth eruption is the process through which teeth …

[HTML][HTML] Primary failure of tooth eruption: Etiology and management

T Yamaguchi, K Hosomichi, T Shirota… - … Dental Science Review, 2022 - Elsevier
Primary failure of eruption (PFE) is a rare disorder defined as incomplete tooth eruption
despite the presence of a clear eruption pathway. PFE is known to be caused by rare …

Single-cell transcriptomic analysis reveals developmental relationships and specific markers of mouse periodontium cellular subsets

M Nagata, AKY Chu, N Ono, JD Welch… - Frontiers in dental …, 2021 - frontiersin.org
The periodontium is essential for supporting the functionality of the tooth, composed of
diversity of mineralized and non-mineralized tissues such as the cementum, the periodontal …

Epigenetic regulation in oral squamous cell carcinoma microenvironment: a comprehensive review

H Mesgari, S Esmaelian, K Nasiri, S Ghasemzadeh… - Cancers, 2023 - mdpi.com
Simple Summary This comprehensive review focuses on the role of epigenetics in oral
squamous cell carcinoma (OSCC), a prevalent type of oral cancer. The review highlights the …

Pth1r signal in Gli1+ cells maintains postnatal cranial base synchondrosis

K Amano, Y Kitaoka, S Kato… - Journal of dental …, 2023 - journals.sagepub.com
Cranial base synchondroses are the endochondral ossification centers for cranial base
growth and thus indispensable for proper skull, brain, and midfacial development. The …

Validating clinical characteristics of primary failure of eruption (PFE) associated with PTH1R variants

C Grippaudo, I D'Apolito, C Cafiero, A Re… - Progress in …, 2021 - Springer
Background Primary failure of eruption (PFE) is a hereditary condition, and linkage with
variants in the PTH1R gene has been demonstrated in many cases. The clinical severity and …

Diverse stem cells for periodontal tissue formation and regeneration

M Nagata, JD English, N Ono, W Ono - genesis, 2022 - Wiley Online Library
The periodontium is comprised of multiple units of mineralized and nonmineralized tissues
including the cementum on the root surface, the alveolar bone, periodontal ligament (PDL) …

Effects of antiresorptive medications on tooth root formation and tooth eruption in paediatric patients

Y Arai, JD English, N Ono, W Ono - Orthodontics & craniofacial …, 2023 - Wiley Online Library
Tooth eruption is a pivotal milestone for children's growth and development. This process
involves with the formation of the tooth root, the periodontal ligament (PDL) and the alveolar …