Management of rheumatoid arthritis: an overview

AF Radu, SG Bungau - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology,
primarily affecting the joints, then extra-articular manifestations can occur. Due to its …

Immunopathogenesis of rheumatoid arthritis

GS Firestein, IB McInnes - Immunity, 2017 - cell.com
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of
evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an …

The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting

V Malmström, AI Catrina, L Klareskog - Nature Reviews Immunology, 2017 - nature.com
Patients with rheumatoid arthritis can be divided into two major subsets characterized by the
presence versus absence of antibodies to citrullinated protein antigens (ACPAs) and of …

Is the epidemiology of rheumatoid arthritis changing? Results from a population-based incidence study, 1985–2014

E Myasoedova, J Davis, EL Matteson… - Annals of the rheumatic …, 2020 - ard.bmj.com
Objectives To examine trends in the incidence of rheumatoid arthritis (RA) from 2005 to
2014 overall and by serological status as compared with 1995–2004 and 1985–1994 …

Rheumatoid arthritis-related interstitial lung disease: associations, prognostic factors and physiological and radiological characteristics—a large multicentre UK study

CA Kelly, V Saravanan, M Nisar, S Arthanari… - …, 2014 - academic.oup.com
Objectives. The prevalence of interstitial lung disease (ILD) in RA is∼ 5%. Previous work
identified increasing age, active articular disease and articular damage as risk factors for RA …

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

J Shi, R Knevel, P Suwannalai… - Proceedings of the …, 2011 - National Acad Sciences
Autoimmune responses against posttranslationally modified antigens are a hallmark of
several autoimmune diseases. For example, antibodies against citrullinated protein antigens …

Autoantibodies and B Cells: The ABC of rheumatoid arthritis pathophysiology

M Volkov, KA van Schie… - Immunological …, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …

Autoantibodies in rheumatoid arthritis: historical background and novel findings

MV Sokolova, G Schett, U Steffen - Clinical reviews in allergy & …, 2022 - Springer
Autoantibodies represent a hallmark of rheumatoid arthritis (RA), with the rheumatoid factor
(RF) and antibodies against citrullinated proteins (ACPA) being the most acknowledged …

Association of combined exposure to ambient air pollutants, genetic risk, and incident rheumatoid arthritis: a prospective cohort study in the UK Biobank

J Zhang, XY Fang, J Wu, YG Fan… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Evidence for a potential link between air pollution and rheumatoid arthritis (RA)
is inconsistent, and the modified effect of genetic susceptibility on the relationship between …

Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies

D Sugiyama, K Nishimura, K Tamaki, G Tsuji… - Annals of the …, 2010 - ard.bmj.com
Objectives: To assess whether smoking is a risk factor for developing rheumatoid arthritis
(RA). Design: Meta-analysis. Method: Data sources were observational studies that …