The Balance Metabolism Safety Net: Integration of Stress Signals by Interacting Transcriptional Factors in Streptomyces and Related Actinobacteria

JF Martín, P Liras - Frontiers in microbiology, 2020 - frontiersin.org
Soil dwelling Streptomyces species are faced with large variations in carbon or nitrogen
sources, phosphate, oxygen, iron, sulfur, and other nutrients. These drastic changes in key …

Engineering of Streptomyces lividans for heterologous expression of secondary metabolite gene clusters

Y Ahmed, Y Rebets, MR Estévez, J Zapp… - Microbial cell …, 2020 - Springer
Background Heterologous expression of secondary metabolite gene clusters is used to
achieve increased production of desired compounds, activate cryptic gene clusters …

Interactions between plant‐beneficial microorganisms in a consortium: Streptomyces microflavus and Trichoderma harzianum

MI Prigigallo, A Staropoli, F Vinale… - Microbial …, 2023 - Wiley Online Library
The construction of microbial consortia is challenging due to many variables to be
controlled, including the cross‐compatibility of the selected strains and their additive or …

[HTML][HTML] A contradictory action of procoagulant ficin by a fibrinolytic serine protease from Egyptian Ficus carica latex

MB Hamed, MO El-Badry, EI Kandil, IH Borai… - Biotechnology …, 2020 - Elsevier
Ficus carica is one of the most popular and edible plants. Its trees emanate latex of high
medical importance. The well-studied procoagulant effect of ficin is a hallmark of this latex …

Microparticles enhance the formation of seven major classes of natural products in native and metabolically engineered actinobacteria through accelerated …

M Kuhl, C Rückert, L Gläser… - Biotechnology and …, 2021 - Wiley Online Library
Actinobacteria provide a rich spectrum of bioactive natural products and therefore display an
invaluable source towards commercially valuable pharmaceuticals and agrochemicals …

The Transcription Unit Architecture of Streptomyces lividans TK24

Y Lee, N Lee, Y Jeong, S Hwang, W Kim… - Frontiers in …, 2019 - frontiersin.org
Streptomyces lividans is an attractive host for production of heterologous proteins and
secondary metabolites of other Streptomyces species. To fully harness the industrial …

Heterologous expression of lasso peptides with apparent participation in the morphological development in Streptomyces

AO Reyna-Campos, B Ruiz-Villafan… - AMB Express, 2024 - Springer
Lasso peptides, ribosomally synthesized and post-translationally modified peptides, are
primarily produced by bacteria and some archaea. Streptomyces lasso peptides have been …

[HTML][HTML] Unraveling the Role of Cytochrome P450 as a Key Regulator Lantipeptide Production in Streptomyces globisporus

DR Kim, SI Lee, YS Kwak - The Plant Pathology Journal, 2023 - ncbi.nlm.nih.gov
The aim of this study was to investigate the regulation of lantipeptide production in
Streptomyces globisporus SP6C4, which produces the novel antifungal lantipeptides …

Development of a thiostrepton-free system for stable production of PLD in Streptomyces lividans SBT5

J Wang, H Zhu, H Shang, B Guo, M Zhang… - Microbial Cell …, 2022 - Springer
Abstract Background Phospholipase D (PLD) is highly valuable in the food and medicine
industries, where it is used to convert low-cost phosphatidylcholine into high-value …

Deletions of conserved extracytoplasmic function sigma factors-encoding genes in Streptomyces have a major impact on secondary metabolism

ON Sekurova, M Zehl, M Predl, P Hunyadi… - Microbial Cell …, 2024 - Springer
Background Ethanol shock significantly affects expression of over 1200 genes in
Streptomyces venezuelae NRRL B-65,442, including those involved in secondary …