Systematic review with meta-analysis: safety and effectiveness of combining biologics and small molecules in inflammatory bowel disease

QA Alayo, M Fenster, O Altayar, KL Glassner… - Crohn's & Colitis …, 2022 - academic.oup.com
Background Combining biologics and small molecules could potentially overcome the
plateau of drug efficacy in inflammatory bowel disease (IBD). We conducted a systematic …

The risk for opportunistic infections in inflammatory bowel disease with biologics: an update

ZA Borman, J Côté-Daigneault… - Expert Review of …, 2018 - Taylor & Francis
Introduction: Crohn's disease and Ulcerative Colitis are forms of inflammatory bowel disease
(IBD), chronic diseases treated with medical and surgical therapy. Patients with IBD are …

Dual biologic or small molecule therapy in refractory pediatric inflammatory bowel disease (DOUBLE-PIBD): a multicenter study from the pediatric IBD Porto Group of …

A Yerushalmy-Feler, C Olbjorn, KL Kolho… - Inflammatory Bowel …, 2024 - academic.oup.com
Background Current data on dual biologic therapy in children are limited. This multicenter
study aimed to evaluate the effectiveness and safety of dual therapy in pediatric patients with …

Real-world clinical effectiveness and safety of vedolizumab and anti-tumor necrosis factor alpha treatment in ulcerative colitis and Crohn's disease patients: a German …

U Helwig, M Mross, S Schubert, H Hartmann… - BMC …, 2020 - Springer
Background Real-world comparisons of biologic treatment outcomes for ulcerative colitis
(UC) or Crohn's disease (CD) patients are limited. We sought to evaluate the real-world …

Benefit–risk assessment of vedolizumab in the treatment of Crohn's disease and ulcerative colitis

R Battat, C Ma, V Jairath, R Khanna, BG Feagan - Drug Safety, 2019 - Springer
Vedolizumab, a humanized monoclonal antibody to the α4β7 integrin, reduces lymphocyte
trafficking to the intestine. This gut-selective mechanism of action offers a safer alternative to …

[PDF][PDF] 老年性溃疡性结肠炎患者临床特征及中医证型分布研究

石裕, 卢璐 - 中国中西医结合消化杂志, 2022 - zxyxh.whuhzzs.com
目的: 分析老年性溃疡性结肠炎(UC) 患者的临床类型, 疾病活动度, 既往用药及中医证型分布.
方法: 收集2018 年8 月—2021 年7 月在上海中医药大学附属龙华医院脾胃病科住院及门诊治疗 …

Should we use anti-tumor necrosis factor agents or vedolizumab as first-line biological therapy in ulcerative colitis?

L Pouillon, J Van Stappen, P Bossuyt, S Danese… - Best Practice & …, 2018 - Elsevier
Randomized controlled trials with direct comparisons between the different available
biological agents in ulcerative colitis are lacking. The comparative efficacy, safety and …

Актуальна ли терапия инфликсимабом в настоящее время у пациентов с воспалительными заболеваниями кишечника?(обзор литературы)

ТЛ Александров, БА Выкова - Колопроктология, 2024 - ruproctology.com
Аннотация ВВЕДЕНИЕ: в настоящее время в лечении среднетяжёлых форм
воспалительных заболеваний кишечника (ВЗК) активно используются генно …

Vedolizumab combined with surgical resection successfully treated perforating Crohn's disease with peritoneal space to rectal and vaginal fistulas: a case report

MW Chung, CM Chen, JT Hsu, RC Wu, CT Chiu… - BMC …, 2021 - Springer
Background Intestinal perforations and fistulas are common complications of Crohn's
disease. However, chronic perforation with peritoneal space to rectal and vaginal fistulas …

Clinical characteristics and TCM syndrome distribution of elderly patients with ulcerative colitis

SHI Yu, LU Lu - Chin J Integr Tradit West Med Dig, 2022 - zxyxhen.whuhzzs.com
Clinical characteristics and TCM syndrome distribution of elderly patients with ulcerative
colitis Homepage Journals 1.{{journal.titleEn}} {{journal.titleEn}} {{journal.titleEn}} {{journal.titleEn}} …