[HTML][HTML] miR-223: an inflammatory oncomiR enters the cardiovascular field

F Taïbi, V Metzinger-Le Meuth, ZA Massy… - … et Biophysica Acta (BBA …, 2014 - Elsevier
MicroRNAs (miRNAs) are small, noncoding RNAs of 18–22 nucleotides in length that
regulate post-transcriptional expression by base-pairing with target mRNAs. It is now clearly …

Advances in molecular biomarkers for gastric cancer: miRNAs as emerging novel cancer markers

HH Wu, W Lin, KW Tsai - Expert reviews in molecular medicine, 2014 - cambridge.org
Carcinoma of the stomach is one of the most prevalent cancer types in the world. Although
the incidence of gastric cancer is declining, the outcomes of gastric cancer patients remain …

[HTML][HTML] Circulating microRNAs and long non-coding RNAs in gastric cancer diagnosis: an update and review

YK Huang, JC Yu - World journal of gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the fourth most common cancer and the third leading cause of cancer
mortality worldwide. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are the …

Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells

S Masciarelli, G Fontemaggi, S Di Agostino, S Donzelli… - Oncogene, 2014 - nature.com
Mutant p53 proteins are expressed at high frequency in human tumors and are associated
with poor clinical prognosis and resistance to chemotherapeutic treatments. Here we show …

Serum levels of miR-126 and miR-223 and outcomes in chronic kidney disease patients

O Fourdinier, E Schepers, V Metzinger-Le Meuth… - Scientific reports, 2019 - nature.com
Several microRNAs (miRNAs) have been linked to chronic kidney disease (CKD) mortality,
cardiovascular (CV) complications and kidney disease progression. However, their …

The many facets of miR‐223 in cancer: oncosuppressor, oncogenic driver, therapeutic target, and biomarker of response

A Favero, I Segatto, T Perin… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Given their intrinsic pleiotropism, microRNAs (miR) play complex biological roles, in both
normal and pathological conditions. Often the same miR can act as oncogene or …

Downregulation of miR-223 expression is an early event during mammary transformation and confers resistance to CDK4/6 inhibitors in luminal breast cancer

F Citron, I Segatto, GLR Vinciguerra, L Musco, F Russo… - Cancer research, 2020 - AACR
Abstract miR-223 is an anti-inflammatory miRNA that in cancer acts either as an
oncosuppressor or oncopromoter, in a context-dependent manner. In breast cancer, we …

Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma

W Kang, JHM Tong, RWM Lung, Y Dong, J Zhao… - Molecular cancer, 2015 - Springer
Background MicroRNAs (miRNAs) have been reported to play an important role in
tumorigenesis. In this study, the role of miR-15a and miR-16-1 in gastric adenocarcinoma …

Small molecules targeting microRNA for cancer therapy: Promises and obstacles

D Wen, M Danquah, AK Chaudhary… - Journal of Controlled …, 2015 - Elsevier
Aberrant expression of miRNAs is critically implicated in cancer initiation and progression.
Therapeutic approaches focused on regulating miRNAs are therefore a promising approach …

Exosomal CXCL14 Contributes to M2 Macrophage Polarization through NF‐κB Signaling in Prostate Cancer

HY Tian, Q Liang, Z Shi, H Zhao - Oxidative Medicine and …, 2022 - Wiley Online Library
Chemokine (C‐X‐C motif) ligand 14 (CXCL14) plays a critical role in maintaining
homeostasis and inflammation in the local cell environment and regulating cancer …