[HTML][HTML] Microfluidic platforms for cell cultures and investigations

ML Coluccio, G Perozziello, N Malara, E Parrotta… - Microelectronic …, 2019 - Elsevier
This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …

[HTML][HTML] Fluid shear stress and tumor metastasis

Q Huang, X Hu, W He, Y Zhao, S Hao… - American journal of …, 2018 - ncbi.nlm.nih.gov
The tumor microenvironment (TME) is a key factor regulating tumor cell invasion and
metastasis. The effects of biochemical factors such as stromal cells, immune cells, and …

[HTML][HTML] Integrated microfluidic device for single-cell trapping and spectroscopy

C Liberale, G Cojoc, F Bragheri, P Minzioni… - Scientific reports, 2013 - nature.com
Optofluidic microsystems are key components towards lab-on-a-chip devices for
manipulation and analysis of biological specimens. In particular, the integration of optical …

HIF‐1, the Warburg Effect, and Macrophage/Microglia Polarization Potential Role in COVID‐19 Pathogenesis

E Ferraro, M Germanò, R Mollace… - Oxidative Medicine …, 2021 - Wiley Online Library
Despite the international scientific community's commitment to improve clinical knowledge
about coronavirus disease 2019 (COVID‐19), knowledge regarding molecular details …

Advances of microfluidics in biomedical engineering

Q Zhong, H Ding, B Gao, Z He… - Advanced materials …, 2019 - Wiley Online Library
As an enabling technique, microfluidic systems have developed rapidly in recent years to
emerge as a powerful tool in the field of biomedical engineering. Microfluidics enables …

[HTML][HTML] Three-dimensional culture models to study innate anti-tumor immune response: advantages and disadvantages

A Poggi, F Villa, JLC Fernadez, D Costa, MR Zocchi… - Cancers, 2021 - mdpi.com
Simple Summary The classical approach to study the immune response against a tumor was
mixing immune cells with tumor cell suspensions in several experimental settings. These …

Evolving tumor characteristics and smart nanodrugs for tumor immunotherapy

W Sun, S Xie, SF Liu, X Hu, D Xing - International Journal of …, 2024 - Taylor & Francis
Typical physiological characteristics of tumors, such as weak acidity, low oxygen content,
and upregulation of certain enzymes in the tumor microenvironment (TME), provide survival …

Microfluidic technologies in cell isolation and analysis for biomedical applications

J Wu, Q Chen, JM Lin - Analyst, 2017 - pubs.rsc.org
Efficient platforms for cell isolation and analysis play an important role in applied and
fundamental biomedical studies. As cells commonly have a size of around 10 microns …

Microfluidic device for continuous single cells analysis via Raman spectroscopy enhanced by integrated plasmonic nanodimers

G Perozziello, P Candeloro, A De Grazia, F Esposito… - Optics …, 2016 - opg.optica.org
In this work a Raman flow cytometer is presented. It consists of a microfluidic device that
takes advantages of the basic principles of Raman spectroscopy and flow cytometry. The …

[HTML][HTML] A passive microfluidic device for chemotaxis studies

ML Coluccio, MA D'Attimo, CM Cristiani, P Candeloro… - Micromachines, 2019 - mdpi.com
This work presents a disposable passive microfluidic system, allowing chemotaxis studies,
through the generation of a concentration gradient. The device can handle liquid flows …