The tissue-specific transcriptional landscape underlines the involvement of endothelial cells in health and disease

S Parab, E Setten, E Astanina, F Bussolino… - Pharmacology & …, 2023 - Elsevier
Endothelial cells (ECs) that line vascular and lymphatic vessels are being increasingly
recognized as important to organ function in health and disease. ECs participate not only in …

Bone marrow niches for hematopoietic stem cells

AL Pereira, S Galli, C Nombela‐Arrieta - HemaSphere, 2024 - Wiley Online Library
Hematopoietic stem cells (HSCs) are the cornerstone of the hematopoietic system. HSCs
sustain the continuous generation of mature blood derivatives while self‐renewing to …

Low Kit expression identifies Hematopoietic Stem Cell subsets with enhanced lymphoid potential in mice and humans

HK Elias, S Mitra, MB da Silva, A Rajagopalan… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Hematopoietic stem cells (HSCs) with multilineage potential are critical for effective T cell
reconstitution and restoration of the adaptive immune system after allogeneic Hematopoietic …

Endomucin knockout leads to delayed retinal vascular development and reduced ocular pathological neovascularization

Z Hu, I Cano, A Lennikov, M Wild, U Gupta, EYS Ng… - bioRxiv, 2024 - biorxiv.org
Endomucin (EMCN), an endothelial-specific glycocalyx component highly expressed in
capillary and venous endothelium, plays a critical role in regulating VEGF receptor 2 …