Neanderthals, our closest extinct relatives, lived in western Eurasia from 400,000 years ago
until they went extinct around 40,000 years ago. DNA retrieved from ancient specimens …

Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …

Genotype× environment interactions (GxE) have long been recognized as a key mechanism
underlying human phenotypic variation. Technological developments over the past 15 years …

Single-nucleotide polymorphism rs71327024 located in the human 3p21. 31 locus has been
associated with an elevated risk of hospitalization upon SARS-CoV-2 infection. The 3p21 …

Neanderthal and Denisovan hybridisation with modern humans has generated a non-
random genomic distribution of introgressed regions, the result of drift and selection …

Admixture occurs between different ethnic human populations. The global colonization in
recent centuries by Europeans led to the most significant admixture in human history. While …

The admixture between modern humans and Neandertals has resulted in∼ 2% of the
genomes of present-day non-Africans being composed of Neandertal DNA. Introgressed …

Since the outbreak of COVID-19, genome-wide association studies have tried to discover
the role of genetic predisposition in the clinical variability of this viral infection. The findings …

Background Genome-wide association studies of COVID-19 severity have been carried out
mostly on European or East Asian populations with small representation of other world …

The admixture between modern humans and Neandertals has resulted in∼ 2% of the
genomes of present-day non-Africans being composed of Neandertal DNA. Introgressed …