[HTML][HTML] Platinum-based drugs for cancer therapy and anti-tumor strategies

C Zhang, C Xu, X Gao, Q Yao - Theranostics, 2022 - ncbi.nlm.nih.gov
Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for
chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Photodynamic therapy—current limitations and novel approaches

G Gunaydin, ME Gedik, S Ayan - Frontiers in Chemistry, 2021 - frontiersin.org
Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …

Designing bioresponsive nanomaterials for intracellular self-assembly

S Chagri, DYW Ng, T Weil - Nature Reviews Chemistry, 2022 - nature.com
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

Activatable fluorescent probes for real-time imaging-guided tumor therapy

QJ Duan, ZY Zhao, YJ Zhang, L Fu, YY Yuan… - Advanced Drug Delivery …, 2023 - Elsevier
Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021 - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

Nanoprobe-based molecular imaging for tumor stratification

X Ma, M Mao, J He, C Liang, HY Xie - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Toward multi-targeted platinum and ruthenium drugs—a new paradigm in cancer drug treatment regimens?

RG Kenny, CJ Marmion - Chemical reviews, 2019 - ACS Publications
While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …