The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

Metabolomics is undergoing tremendous growth and is being employed to solve a diversity
of biological problems from environmental issues to the identification of biomarkers for …

Urine metabolomics is widely used for biomarker research in the fields of medicine and
toxicology. As a consequence, characterization of the variations of the urine metabolome …

Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

Proton nuclear magnetic resonance (NMR)-based metabolic phenotyping of urine and blood
plasma/serum samples provides important prognostic and diagnostic information and …

Metabolic profiling, metabolomic and metabonomic studies mainly involve the
multicomponent analysis of biological fluids, tissue and cell extracts using NMR …

For the analysis of the spectra of complex biofluids, preprocessing methods play a crucial
role in rendering the subsequent data analyses more robust and accurate. Normalization is …

Classifying groups of individuals based on their metabolic profile is one of the main topics in
metabolomics research. Due to the low number of individuals compared to the large number …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

The emerging field of metabolomics, in which a large number of small-molecule metabolites
from body fluids or tissues are detected quantitatively in a single step, promises immense …