Deep vein thrombosis (DVT) is a major origin of morbidity and mortality. While DVT has long
been considered as blood coagulation disorder, several recent lines of evidence …

Venous thromboembolism is a very common and costly health problem worldwide.
Anticoagulant treatment for VTE is imperfect: all have the potential for significant bleeding …

Acute respiratory distress syndrome (ARDS), the most severe form of acute lung injury, is
associated with reduced lung compliance and hypoxemia. Curcumin exhibits potent anti …

Abstract Toll-like receptor 3 (TLR3) is a pathogen recognition molecule associated with viral
infection with double-stranded RNA (dsRNA) as its ligand. We evaluated the role of TLR3 in …

Aims Endotoxin induced acute lung injury (ALI) is a critical complication of some clinical
illnesses. Endothelial cell dysfunction and excessive pro-inflammation cytokine release are …

Objective Venous thromboembolism (VTE) is reported to occur in up to 33% of patients
undergoing major vascular surgery. Despite this high incidence, patients inconsistently …

Venous thromboembolism (VTE) is a complex, multifactorial life-threatening disease that
involves vascular endothelial cell (VEC) dysfunction. However, the exact pathogenesis and …

Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and
pulmonary embolism (PE), may affect up to 900,000 patients per year, resulting in …

The incidence of thrombosis is dramatically enhanced in sepsis patients and under
conditions of hypoxia (reduced oxygenation), but the mechanisms that regulate sepsis …

2021-12-16 Assigned to THE REGENTS OF THE UNIVERSITY OF MICHIGAN reassignment
THE REGENTS OF THE UNIVERSITY OF MICHIGAN ASSIGNMENT OF ASSIGNORS …