Inwardly rectifying potassium channels: their structure, function, and physiological roles

H Hibino, A Inanobe, K Furutani… - Physiological …, 2010 - journals.physiology.org
Inwardly rectifying K+ (Kir) channels allow K+ to move more easily into rather than out of the
cell. They have diverse physiological functions depending on their type and their location …

KATP Channels in the Cardiovascular System

MN Foster, WA Coetzee - Physiological reviews, 2016 - journals.physiology.org
KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

Cardiac ionic currents and acute ischemia: from channels to arrhythmias

E Carmeliet - Physiological reviews, 1999 - journals.physiology.org
The aim of this review is to provide basic information on the electrophysiological changes
during acute ischemia and reperfusion from the level of ion channels up to the level of …

ATP-sensitive and inwardly rectifying potassium channels in smooth muscle

JM Quayle, MT Nelson… - Physiological reviews, 1997 - journals.physiology.org
The properties and roles of ATP-sensitive (KATP) and inwardly rectifying (KIR) potassium
channels are reviewed. Potassium channels regulate the membrane potential of smooth …

Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise

OM Sejersted, G Sjøgaard - Physiological reviews, 2000 - journals.physiology.org
Since it became clear that K+ shifts with exercise are extensive and can cause more than a
doubling of the extracellular [K+]([K+] s) as reviewed here, it has been suggested that these …

Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

K Ho, CG Nichols, WJ Lederer, J Lytton, PM Vassilev… - Nature, 1993 - nature.com
A complementary DNA encoding an ATP-regulated potassium channel has been isolated by
expression cloning from rat kidney. The predicted 45K protein, which features two potential …

[HTML][HTML] Toward understanding the assembly and structure of KATP channels

L Aguilar-Bryan, JP CLEMENT IV… - Physiological …, 1998 - journals.physiology.org
Abstract Aguilar-Bryan, Lydia, John P. Clement IV, Gabriela Gonzalez, Kumud Kunjilwar,
Andrey Babenko, and Joseph Bryan. Toward Understanding the Assembly and Structure of …

ATP-Sensitive potassium channels and their physiological and pathophysiological roles.

A Tinker, Q Aziz, Y Li, M Specterman - Compr Physiol, 2018 - qmro.qmul.ac.uk
ATP sensitive potassium channels (KATP) are so named because they open as cellular ATP
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …

Octameric Stoichiometry of the KATP Channel Complex

SL Shyng, CG Nichols - The Journal of general physiology, 1997 - rupress.org
ATP-sensitive potassium (KATP) channels link cellular metabolism to electrical activity in
nerve, muscle, and endocrine tissues. They are formed as a functional complex of two …

Membrane Phospholipid Control of Nucleotide Sensitivity of KATP Channels

SL Shyng, CG Nichols - Science, 1998 - science.org
Adenosine triphosphate (ATP)–sensitive potassium (KATP) channels couple cell
metabolism to electrical activity. Phosphatidylinositol phosphates (PIPs) profoundly …