The ErbB/HER family of protein-tyrosine kinases and cancer

R Roskoski Jr - Pharmacological research, 2014 - Elsevier
The human epidermal growth factor receptor (EGFR) family consists of four members that
belong to the ErbB lineage of proteins (ErbB1–4). These receptors consist of a glycosylated …

[HTML][HTML] Gestational trophoblastic tumours: an update for 2014

FEM Froeling, MJ Seckl - Current oncology reports, 2014 - Springer
Gestational trophoblastic disease describes a variety of pregnancy-related diseases
including the premalignant conditions of a partial and complete hydatidiform mole and the …

[HTML][HTML] Update on the diagnosis and management of gestational trophoblastic disease

HYS Ngan, MJ Seckl, RS Berkowitz, Y Xiang… - International Journal of …, 2015 - Elsevier
Gestational trophoblastic disease (GTD) is a group of uncommon conditions associated with
abnormal pregnancy. Histologically, it includes the benign partial and complete hydatidiform …

[HTML][HTML] Diagnosis, classification and treatment of gestational trophoblastic neoplasia

A Biscaro, A Braga, RS Berkowitz - Revista Brasileira de Ginecologia …, 2015 - SciELO Brasil
Gestational trophoblastic neoplasia (GTN) is the term to describe a set of malignant
placental diseases, including invasive mole, choriocarcinoma, placental site trophoblastic …

[HTML][HTML] SEOM clinical guidelines in gestational trophoblastic disease (2017)

A Santaballa, Y García, A Herrero, N Laínez… - Clinical and …, 2018 - Springer
SEOM clinical guidelines in gestational trophoblastic disease (2017) | Clinical and
Translational Oncology Skip to main content SpringerLink Log in Menu Find a journal Publish …

[HTML][HTML] A review on the pathogenesis and clinical management of placental site trophoblastic tumors

X Feng, Z Wei, S Zhang, Y Du, H Zhao - Frontiers in oncology, 2019 - frontiersin.org
Placental site trophoblastic tumor (PSTT) is a rare type of gestational trophoblastic disease
originating from the intermediate trophoblast. Compared with hydatidiform mole, invasive …

[HTML][HTML] Gestational trophoblastic neoplasia with brain metastasis at initial presentation: a retrospective study

D Gavanier, H Leport, J Massardier, F Abbas… - International journal of …, 2019 - Springer
Objective To evaluate the survival and functional outcome of patients with brain metastasis
due to gestational trophoblastic neoplasia (GTN). Methods A 17-year retrospective study …

Treatment of high-risk gestational trophoblastic neoplasia and chemoresistance/relapsed disease

A Braga, KM Elias, NS Horowitz… - Best Practice & Research …, 2021 - Elsevier
High-risk gestational trophoblastic neoplasia (GTN) has an increased risk of developing
chemoresistance to single-agent chemotherapy; therefore, the primary treatment should be …

Efficacies of FAEV and EMA/CO regimens as primary treatment for gestational trophoblastic neoplasia

M Ji, S Jiang, J Zhao, X Wan, F Feng, T Ren… - British Journal of …, 2022 - nature.com
Background Guidelines recommend etoposide, methotrexate, actinomycin D (EMA)/
cyclophosphamide, vincristine (CO) as first-line treatment for high-risk gestational …

Silibinin stimluates apoptosis by inducing generation of ROS and ER stress in human choriocarcinoma cells

J Ham, W Lim, FW Bazer, G Song - Journal of cellular …, 2018 - Wiley Online Library
Silibinin is a flavonolignan extracted from seeds of milk thistles. Traditionally, it has been
used as a therapeutic agent for liver disorders, and now it is well‐known for its anti‐cancer …