The plant ribosome-inactivating proteins play important roles in defense against pathogens and insect pest attacks
Ribosome-inactivating proteins (RIPs) are toxic N-glycosidases that depurinate eukaryotic
and prokaryotic rRNAs, thereby arresting protein synthesis during translation. RIPs are …
and prokaryotic rRNAs, thereby arresting protein synthesis during translation. RIPs are …
Antiviral activity of ribosome-inactivating proteins
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2. 2.22)
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …
that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs …
Ageritin from pioppino mushroom: The prototype of ribotoxin-like proteins, a novel family of specific ribonucleases in edible mushrooms
Ageritin is a specific ribonuclease, extracted from the edible mushroom Cyclocybe aegerita
(synonym Agrocybe aegerita), which cleaves a single phosphodiester bond located within …
(synonym Agrocybe aegerita), which cleaves a single phosphodiester bond located within …
How ricin damages the ribosome
P Grela, M Szajwaj, P Horbowicz-Drożdżal… - Toxins, 2019 - mdpi.com
Ricin belongs to the group of ribosome-inactivating proteins (RIPs), ie, toxins that have
evolved to provide particular species with an advantage over other competitors in nature …
evolved to provide particular species with an advantage over other competitors in nature …
Structural and functional characterization of the cytotoxic protein ledodin, an atypical ribosome‐inactivating protein from shiitake mushroom (Lentinula edodes)
We have purified ledodin, a cytotoxic 22‐kDa protein from shiitake mushroom (Lentinula
edodes) consisting of a 197 amino acid chain. Ledodin possessed N‐glycosylase activity on …
edodes) consisting of a 197 amino acid chain. Ledodin possessed N‐glycosylase activity on …
Purification, characterization and cytotoxicity assessment of Ageritin: The first ribotoxin from the basidiomycete mushroom Agrocybe aegerita
N Landi, S Pacifico, S Ragucci, R Iglesias… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Several species belonging to Ascomycota phylum produce extracellular
ribonucleases, known as ribotoxins, which exhibit RNase activity through the cleavage of a …
ribonucleases, known as ribotoxins, which exhibit RNase activity through the cleavage of a …
Structures and ribosomal interaction of ribosome-inactivating proteins
Ribosome-inactivating proteins (RIPs) including ricin, Shiga toxin, and trichosanthin, are
RNA N-glycosidases that depurinate a specific adenine residue (A-4324 in rat 28S …
RNA N-glycosidases that depurinate a specific adenine residue (A-4324 in rat 28S …
[HTML][HTML] Quinoa as source of type 1 ribosome inactivating proteins: A novel knowledge for a revision of its consumption
This study investigates on the presence of toxic proteins in quinoa seeds. To this aim, a
plethora of biochemical approaches were adopted for the purification and characterization of …
plethora of biochemical approaches were adopted for the purification and characterization of …
[HTML][HTML] Isolation, characterization and biological action of type-1 ribosome-inactivating proteins from tissues of Salsola soda L.
Ribosome-inactivating proteins (RIPs) are known as RNA N-glycosylases. They depurinate
the major rRNA, damaging ribosomes and inhibiting protein synthesis. Here, new single …
the major rRNA, damaging ribosomes and inhibiting protein synthesis. Here, new single …
Structure and Biological Properties of Ribosome-Inactivating Proteins and Lectins from Elder (Sambucus nigra L.) Leaves
R Iglesias, R Russo, N Landi, M Valletta, A Chambery… - Toxins, 2022 - mdpi.com
Ribosome-inactivating proteins (RIPs) are a group of proteins with rRNA N-glycosylase
activity that catalyze the removal of a specific adenine located in the sarcin–ricin loop of the …
activity that catalyze the removal of a specific adenine located in the sarcin–ricin loop of the …