The potential role of neopterin in Covid-19: a new perspective

HM Al-Kuraishy, AI Al-Gareeb, KJ Alzahrani… - Molecular and Cellular …, 2021 - Springer
Neopterin (NPT) is a member of pteridines group, synthesized by macrophages when
stimulated by interferon gamma (INF-γ). NPT is regarded as a macrophage stimulation …

The importance of neopterin in COVID-19: The prognostic value and relation with the disease severity

Y Rasmi, N Heidari, KK Kırboğa, S Hatamkhani… - Clinical …, 2022 - Elsevier
Abstract Coronavirus Disease 2019 [COVID-19], caused by severe acute respiratory
syndrome coronavirus 2 [SARS-CoV-2], has rapidly evolved into a global health emergency …

Decreased gene expression of Epstein–Barr virus-induced gene 3 (EBI-3) may contribute to the pathogenesis of rheumatoid arthritis

N Iranshahi, S Assar, SM Amiri, P Zafari… - Immunological …, 2019 - Taylor & Francis
ABSTRACT Background: Interleukin-35 (IL-35) is a member of the IL-12 family of
heterodimeric cytokines produced by regulatory T (Treg) cells. This immunosuppressive …

Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study

EM Apalset, CG Gjesdal, PM Ueland… - Clinical & …, 2014 - academic.oup.com
The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune
activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the …

Age, but not anthelmintic treatment, is associated with urinary neopterin levels in semi-free ranging Barbary macaques

N Müller, M Heistermann, C Strube, O Schülke… - Scientific Reports, 2017 - nature.com
Studying host parasite interactions and their implications for evolution and ecology recently
received increasing attention, particularly with regard to host physiology and immunity. Here …

[HTML][HTML] Neopterin derivatives–a novel therapeutic target rather than biomarker for atherosclerosis and related diseases

T Watanabe - Vasa, 2020 - econtent.hogrefe.com
This review provides an updated overview of the emerging roles of neopterin derivatives in
atherosclerosis. Neopterin, a metabolite of guanosine triphosphate, is produced by …

Assessment of serum neopterin and calprotectin as biomarkers for subclinical inflammation in patients with familial Mediterranean fever

D Tezcan, DE Onmaz, A Sivrikaya, S Hakbilen… - Irish Journal of Medical …, 2023 - Springer
Abstract Background Familial Mediterranean fever (FMF) is the most common
autoinflammatory disease characterized by short, repeated, and self-limiting attacks of fever …

Elevated serum levels of neopterin at admission predicts depression after acute ischemic stroke: a 6-month follow-up study

CZ Tang, YL Zhang, WS Wang, WG Li, JP Shi - Molecular neurobiology, 2016 - Springer
Inflammation and cell-mediated immune activation are attributed to the pathogenesis and
pathophysiology in depression. Our aim was to test the possible association between serum …

[HTML][HTML] Ecological, parasitological and individual determinants of plasma neopterin levels in a natural mandrill population

SE Dibakou, A Souza, L Boundenga, L Givalois… - International Journal for …, 2020 - Elsevier
Investigating how individuals adjust their investment into distinct components of the immune
system under natural conditions necessitates to develop immune phenotyping tools that …

Association of neopterin as a marker of immune system activation and juvenile rheumatoid arthritis activity

MMA Shady, HA Fathy, A Ali, ER Youness… - Jornal de …, 2015 - SciELO Brasil
OBJECTIVE: To evaluate neopterin plasma concentrations in patients with active juvenile
idiopathic arthritis (JIA) and correlate them with disease activity. METHODS: Sixty patients …