Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Epidemiology, pathophysiology and contemporary management of cardiogenic shock–a position statement from the Heart Failure Association of the European Society …

O Chioncel, J Parissis, A Mebazaa… - European journal of …, 2020 - Wiley Online Library
Cardiogenic shock (CS) is a complex multifactorial clinical syndrome with extremely high
mortality, developing as a continuum, and progressing from the initial insult (underlying …

Association of race/ethnicity, gender, and socioeconomic status with sodium-glucose cotransporter 2 inhibitor use among patients with diabetes in the US

LA Eberly, L Yang, ND Eneanya, U Essien… - JAMA network …, 2021 - jamanetwork.com
Importance Sodium-glucose cotransporter 2 (SGLT2) inhibitors significantly reduce deaths
from cardiovascular conditions, hospitalizations for heart failure, and progression of kidney …

Screening for hypertension in adults: US Preventive Services Task Force reaffirmation recommendation statement

AH Krist, KW Davidson, CM Mangione, M Cabana… - Jama, 2021 - jamanetwork.com
Importance Hypertension is a prevalent condition that affects approximately 45% of the adult
US population and is the most commonly diagnosed condition at outpatient office visits …

Historical redlining and cardiovascular health: the multi-ethnic study of atherosclerosis

MS Mujahid, X Gao, LP Tabb… - Proceedings of the …, 2021 - National Acad Sciences
We investigated historical redlining, a government-sanctioned discriminatory policy, in
relation to cardiovascular health (CVH) and whether associations were modified by present …

Global, regional, and national burden of ischaemic heart disease and its attributable risk factors, 1990–2017: results from the Global Burden of Disease Study 2017

H Dai, AA Much, E Maor, E Asher… - … Journal-Quality of …, 2022 - academic.oup.com
Aims The aim of this study was to estimate the burden and risk factors for ischaemic heart
disease (IHD) in 195 countries and territories from 1990 to 2017. Methods and results Data …

Advanced heart failure: epidemiology, diagnosis, and therapeutic approaches

LK Truby, JG Rogers - Heart failure, 2020 - jacc.org
In broad terms,“advanced” heart failure describes a clinical syndrome characterized by
persistent or progressive symptoms and ventricular dysfunction despite guideline-directed …

Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics

MAC Depuydt, KHM Prange, L Slenders, T Örd… - Circulation …, 2020 - Am Heart Assoc
Rationale: Atherosclerotic lesions are known for their cellular heterogeneity, yet the
molecular complexity within the cells of human plaques has not been fully assessed …

NLRP3 inflammasome and the IL-1 pathway in atherosclerosis

A Grebe, F Hoss, E Latz - Circulation research, 2018 - Am Heart Assoc
Inflammation is an important driver of atherosclerosis, the underlying pathology of
cardiovascular diseases. Therefore, therapeutic targeting of inflammatory pathways is …

Socioeconomic status and cardiovascular outcomes: challenges and interventions

WM Schultz, HM Kelli, JC Lisko, T Varghese, J Shen… - Circulation, 2018 - Am Heart Assoc
Socioeconomic status (SES) has a measurable and significant effect on cardiovascular
health. Biological, behavioral, and psychosocial risk factors prevalent in disadvantaged …