Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

Maternal and paternal obesity and type 2 diabetes are recognized risk factors for the
development of metabolic dysfunction in offspring, even when the offspring follow a healthful …

Epigenetic changes are caused by biochemical regulators of gene expression that can be
transferred across generations or through cell division. Epigenetic modifications can arise …

Maternal pregnancy nutrition influences fetal growth. Evidence is limited, however, on the
relationship of maternal diet during pregnancy and lactation on infant postnatal growth and …

Obesity is considered a global epidemic. Specifically, obesity during pregnancy programs
an increased risk of the offspring developing metabolic disorders in addition to the adverse …

Background and Objectives Pregnancy causes changes in women's lifestyle; therefore, their
health-promoting behaviors should be improved in order to avoid problems during this …

To prevent the intergenerational transfer of obesity and end the current epidemic,
interventions are needed across the early life stages, from preconception to prenatal to …

Nutritional constraints including not only caloric restriction or protein deficiency, but also
energy-dense diets affect metabolic health and frequently lead to obesity and insulin …

Epigenetics is the study of gene expression changes that occur in the absence of altered
genotype. Current evidence indicates a role for environmentally induced alterations to …

Background: It is well established that maternal exercise during pregnancy improves
metabolic outcomes associated with obesity in mothers and offspring, however, its effects on …