Apoptosis is used by metazoan organisms to dispose of damaged or unnecessary cells
during development, tissue homeostasis, and disease. One of the situations where …

Innate immunity is essential for insects to survive infectious pathogens. In baculovirus-
infected lepidopteran cells, apoptosis and global protein synthesis shutdown are major …

Baculoviruses, members of the family B aculoviridae, are large, enveloped viruses that
contain a double‐stranded circular DNA genome of 80–180 kbp, encoding 90–180 putative …

Baculoviruses, like their holometabolous host insects, comprise a monophyletic clade and,
since the evolutionary origin of this virus family, have coevolved with their hosts. Despite this …

Baculoviruses encode inhibitors of apoptosis (IAPs), which are classified into five groups,
IAP1–5, based on their sequence homology. Most of the baculovirus IAPs with anti-apoptotic …

Hyphantria cunea nucleopolyhedrovirus (HycuNPV) infection protected SpIm cells from
actinomycin D (ActD)-induced apoptosis as early as 4 h postinfection. Analysis by Southern …

Simple Summary Ecdysone is an essential factor affecting host immunity, in addition to
regulating insect metamorphosis. There are two isoforms of ecdysone receptors (EcR) in …

Antiviral immune responses are mainly triggered through the recognition of virus-derived
nucleic acids by host-specific pattern recognition receptors (PRRs). Here, we identified and …

We cloned and characterized a novel Bombyx mori homologue (bm-dronc) of Drosophila
melanogaster dronc (dm-dronc), which could encode a polypeptide of 438 amino acid …

Baculoviruses are double-stranded circular DNA viruses that infect arthropods via the
midgut. Because of their superiority as eukaryotic expression systems and their importance …