Conspectus Atropisomers, arising from conformational restriction, are inherently chiral due
to the intersecting dissymmetric planes. Since there are numerous applications of …

This tutorial review provides a systematic overview of the available methodologies for the
atroposelective transformation of (heterobiaryl) biaryl precursors toward the synthesis of …

Atropisomeric molecules have found proven applications and have shown promising
potential in chemistry and medicine. The design of N‐heterocyclic carbene (NHC) catalyzed …

Conspectus Axially chiral compounds have received much attention from chemists because
of their widespread appearance in natural products, biologically active compounds, and …

Axial chirality widely exists in natural products, pharmaceutical compounds, and other
functional molecules; these axially chiral compounds also find wide utility as catalysts or …

The construction of N–N axially chiral motifs is an important research topic, owing to their
wide occurrence in natural products, pharmaceuticals and chiral ligands. One efficient …

The catalytic enantioselective assembly of spirocyclic molecules featuring a spiro quaternary
carbon stereocenter is currently of great interest because such privileged 3D structures are …

Axially chiral diaryl ethers, a distinguished class of atropisomers possessing unique dual C−
O axis, hold immense potential for diverse research domains. In contrast to the catalytic …

N-Heterocyclic carbenes (NHCs) belong to the popular family of organocatalysts used in a
wide range of reactions, including that for the synthesis of complex natural products and …

Axial chirality is a key feature of many important organic molecules, such as biologically
active compounds, stereogenic ligands and optically pure materials. Significant efforts in the …