Increasing scientific attention is focused on the gut‐brain axis, including the ability of the
gastrointestinal (GI) tract to modulate central nervous system function. Changes in the …

We investigated relationships among immune, metabolic, and sleep abnormalities in mice
with non-metastatic mammary cancer. Tumor-bearing mice displayed interleukin-6 (IL-6) …

Ganoderma lucidum (Lingzhi) polysaccharide peptide (GL-pp) is a component of the
globally acknowledged traditional Chinese medicine Ganoderma lucidum; Ganoderma …

Breast cancer survivors receiving chemotherapy often report increased anxiety and
depression. However, the mechanism underlying chemotherapy-induced changes in affect …

Chemotherapy is a widely used treatment for a variety of solid and hematological
malignancies. Despite its success in improving the survival rate of cancer patients …

Chemotherapy is more effective in the treatment of peripheral tumors than brain metastases,
likely reflecting the reduced ability of chemotherapy to cross the blood-brain barrier (BBB) …

Cancer is a systemic disease. In order to fully understand it, we must take a holistic view on
how cancer interacts with its host. The brain monitors and responds to natural and aberrant …

The present study was undertaken to explore the possible mechanisms of the behavioral
alterations that develop in response to cancer and to cancer therapy. For this purpose we …

Background Cancer survivors can experience long lasting fatigue resulting in a lower quality
of life. How chemotherapy treatment contributes to this fatigue is poorly understood …

Cancer represents a novel homeostatic challenge to the host system. How the brain senses
and responds to changes in peripheral physiology elicited by tumor growth is a largely …