Polyphenols are secondary metabolites of plants. They comprise several antioxidant
compounds and they are generally considered to be involved in the defense against human …

Monocytes and macrophages are important cells of the innate immune system that have
diverse functions, including defense against invading pathogens, removal of dead cells by …

Aging is inevitable, but the inherently and genetically programmed aging process is
markedly influenced by environmental factors. All organisms are constantly exposed to …

Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing
the scurvy disease, and became very popular for its antioxidant properties. It is an important …

Parkinson disease (PD) is a neurodegenerative disease characterized by progressive
dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The …

Parkinson's disease (PD) is the second most frequent age-related neurodegenerative
disorder. Sex is an important factor in the development of PD, as reflected by the fact that it is …

Oxidative stress reflects an imbalance between the production of reactive oxygen species
(ROS) and antioxidant defense systems, and it can be associated with the pathogenesis and …

The essential trace element selenium, as selenocysteine, is incorporated into antioxidant
selenoproteins such as glutathione peroxidases (GPx), thioredoxin reductases (TrxR) and …

The central nervous system is particularly sensitive to oxidative stress due to many reasons,
including its high oxygen consumption even under basal conditions, high production of …

Parkinson's disease (PD) is a chronic, progressive, and the second most common form of
neurodegenerative disorders. In order to explore novel agents for the treatment of PD, in the …