Polyphenols in health and disease: gut microbiota, bioaccessibility, and bioavailability

J Bié, B Sepodes, PCB Fernandes, MHL Ribeiro - Compounds, 2023 - mdpi.com
Polyphenolic compounds (PC) are among the most abundant secondary metabolites in
nature. They are widely distributed in the world and can be found in fruits, cereals, tea …

Genome-resolved metagenomics: a game changer for microbiome medicine

N Kim, J Ma, W Kim, J Kim, P Belenky… - Experimental & Molecular …, 2024 - nature.com
Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …

Bacterial SNPs in the human gut microbiome associate with host BMI

L Zahavi, A Lavon, L Reicher, S Shoer, A Godneva… - Nature medicine, 2023 - nature.com
Genome-wide association studies (GWASs) have provided numerous associations between
human single-nucleotide polymorphisms (SNPs) and health traits. Likewise, metagenome …

The Gum–Gut axis: periodontitis and the risk of gastrointestinal cancers

G Baima, DG Ribaldone, F Romano, M Aimetti… - Cancers, 2023 - mdpi.com
Simple Summary Periodontitis, a chronic inflammatory disease of the gums, and the oral
microbiome have been recently implicated in the development of various cancers. Due to …

Shigella flexneri utilizes intestinal signals to control its virulence

R Chowdhury, PDP Bitar, KE Bell, C Altier - Gut Microbes, 2023 - Taylor & Francis
The enteric pathogens have evolved to utilize elements from their surroundings to optimize
their infection strategies. A common mechanism to achieve this is to employ intestinal …

Winds of change a tale of: asthma and microbiome

D Galeana-Cadena, IA Gómez-García… - Frontiers in …, 2023 - frontiersin.org
The role of the microbiome in asthma is highlighted, considering its influence on immune
responses and its connection to alterations in asthmatic patients. In this context, we review …

The gut microbiota links disease to human genome evolution

Y Quan, KX Zhang, HY Zhang - Trends in Genetics, 2023 - cell.com
A large number of studies have established a causal relationship between the gut
microbiota and human disease. In addition, the composition of the microbiota is substantially …

The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum

M Byndloss, S Devkota, F Duca, JH Niess… - Diabetes, 2024 - diabetesjournals.org
This article summarizes the state of the science on the role of the gut microbiota (GM) in
diabetes from a recent international expert forum organized by Diabetes, Diabetes Care …

Discovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant …

WK Mousa, R Ghemrawi, T Abu-Izneid… - International journal of …, 2023 - mdpi.com
The human body is a superorganism that harbors trillions of microbes, most of which inhabit
the gut. To colonize our bodies, these microbes have evolved strategies to regulate the …

The landscape and perspectives of the human gut metaproteomics

Z Sun, Z Ning, D Figeys - Molecular & Cellular Proteomics, 2024 - ASBMB
The human gut microbiome is closely associated with human health and diseases.
Metaproteomics has emerged as a valuable tool for studying the functionality of the gut …