BACKGROUND Adaptation of the maternal immune response to accommodate the semi-
allogeneic fetus is necessary for pregnancy success, and disturbances in maternal tolerance …

Seminal fluid is often assumed to have just one function in mammalian reproduction,
delivering sperm to fertilize oocytes. But seminal fluid also transmits signaling agents that …

Purpose We investigated the combination of lymphodepleting chemotherapy followed by the
adoptive transfer of autologous tumor reactive lymphocytes for the treatment of patients with …

Dendritic cells (DCs) include a heterogeneous family of professional APCs involved in
initiation of immunity and in immunologic tolerance. Specifically, peripheral tolerance can be …

Suppression by T regulatory (Tr) cells is essential for the induction of peripheral tolerance.
Many types of CD4+ Tr cells have been described in a number of systems, and although the …

Around 1–5% of all couples experience recurrent pregnancy loss (RPL). Established risk
factors include anatomical, genetic, endocrine, and hemostatic alterations. With around 50 …

Regulatory T cells (Tregs) that constitutively express FOXP3 are instrumental to the
maintenance of tolerance and may suppress graft-versus-host disease (GVHD) in humans …

In recent years, several investigators have unraveled a previously unrecognized role for G-
CSF in the regulation of T cell and dendritic cell functions. The experimental evidence in …

Several hematopoietic growth factors, including interleukin-10 (IL-10) and transforming
growth factor-β1 (TGF-β1), promote the differentiation of tolerogenic dendritic cells (DCs) …

Aims Recent data suggest that the administration of bone marrow-derived stem cells
(BMSC) might improve myocardial perfusion and left ventricular (LV) function after acute …