Psychedelics and psychedelic-assisted psychotherapy

CM Reiff, EE Richman, CB Nemeroff… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …

Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi - Pharmacological Reviews, 2021 - ASPET
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Distinct acute effects of LSD, MDMA, and d-amphetamine in healthy subjects

F Holze, P Vizeli, F Müller, L Ley, R Duerig… - …, 2020 - nature.com
Lysergic acid diethylamide (LSD) is a classic psychedelic, 3, 4-
methylenedioxymethamphetamine (MDMA) is an empathogen, and d-amphetamine is a …

[HTML][HTML] Reduction in social anxiety after MDMA-assisted psychotherapy with autistic adults: a randomized, double-blind, placebo-controlled pilot study

AL Danforth, CS Grob, C Struble, AA Feduccia… - …, 2018 - Springer
Objectives To explore feasibility and safety of MDMA-assisted psychotherapy for reduction of
social fear and avoidance that are common in the autistic population. Methods Autistic adults …

Breakthrough for trauma treatment: safety and efficacy of MDMA-assisted psychotherapy compared to paroxetine and sertraline

AA Feduccia, L Jerome, B Yazar-Klosinski… - Frontiers in …, 2019 - frontiersin.org
Unsuccessfully treated posttraumatic stress disorder (PTSD) is a serious and life-threatening
disorder. Two medications, paroxetine hydrochloride and sertraline hydrochloride, are …

The safety and efficacy of±3, 4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder …

MC Mithoefer, MT Wagner… - Journal of …, 2011 - journals.sagepub.com
Case reports indicate that psychiatrists administered±3, 4-
methylenedioxymethamphetamine (MDMA) as a catalyst to psychotherapy before …

MDMA-assisted psychotherapy for treatment of anxiety and other psychological distress related to life-threatening illnesses: a randomized pilot study

PE Wolfson, J Andries, AA Feduccia, L Jerome… - Scientific reports, 2020 - nature.com
The success of modern medicine creates a growing population of those suffering from life-
threatening illnesses (LTI) who often experience anxiety, depression, and existential …

Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3, 4-methylenedioxymethamphetamine …

MC Mithoefer, MT Wagner… - Journal of …, 2013 - journals.sagepub.com
We report follow-up data evaluating the long-term outcomes for the first completed trial of 3,
4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for chronic, treatment …

[HTML][HTML] MDMA-assisted psychotherapy for PTSD: are memory reconsolidation and fear extinction underlying mechanisms?

AA Feduccia, MC Mithoefer - Progress in neuro-psychopharmacology and …, 2018 - Elsevier
MDMA-assisted psychotherapy for treatment of PTSD has recently progressed to Phase 3
clinical trials and received Breakthrough Therapy designation by the FDA. MDMA used as …

Novel psychopharmacological therapies for psychiatric disorders: psilocybin and MDMA

MC Mithoefer, CS Grob, TD Brewerton - The Lancet Psychiatry, 2016 - thelancet.com
phosphorloxy-N, N-dimethyltryptamine (psilocybin) and methylenedioxymethamfetamine
(MDMA), best known for their illegal use as psychedelic drugs, are showing promise as …