Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …

Introduction: Only a few medications are available for the treatment of alcohol use disorders
(AUDs). Areas covered: This paper discusses approved AUD medications, including the …

Binge alcohol consumption induces discrete social and arousal disturbances in human
populations that promote increased drinking and accelerate the progression of Alcohol Use …

Background People with alcohol use disorder (AUD) may be at higher risk for COVID‐19.
Angiotensin‐converting enzyme 2 (ACE2) and transmembrane serine protease 2 …

Alcohol use disorder needs more effective treatments because relapse rates remain high.
Psychedelics, such as ayahuasca, have been used to treat substance use disorders. Our …

Excessive serotonin (5-HT) signaling plays a critical role in the etiology of alcohol use
disorder. The central nucleus of the amygdala (CeA) is a key player in alcohol-dependence …

Ibogaine is a plant-derived alkaloid and dissociative psychedelic that demonstrates anti-
addictive properties with several substances of abuse, including alcohol. 5-methoxy-N, N …

Drug addiction is a complex disorder that is characterized by compulsivity to seek and take
the drug, loss of control in limiting intake of the drug, and emergence of a withdrawal …

The comorbidity of generalized anxiety disorders (GAD) with alcohol use disorders (AUD) is
common and there is an association between the serotonin transporter (SERT) genetic …

Serotonin (5-hydroxytryptamine; 5-HT) coordinates behavioral responses to stress through a
variety of presynaptic and postsynaptic receptors distributed across functionally diverse …