Cilia mediate an astonishing diversity of processes. Recent advances provide unexpected
insights into the regulatory mechanisms of cilium formation, and reveal diverse regulatory …

Essential to development, primary cilia are microtubule-based cellular organelles that
protrude from the surface of cells. Acting as cellular antenna, primary cilia play central roles …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

The life cycle of a primary cilium begins in quiescence and ends prior to mitosis. In quiescent
cells, the primary cilium insulates itself from contiguous dynamic membrane processes on …

It has been known for some time that atherosclerotic lesions preferentially develop in areas
exposed to low SS and are characterized by a proinflammatory, apoptotic, and senescent …

During autophagy, cytosolic cargo is sequestered into double-membrane vesicles called
autophagosomes. The contributions of specific lipids, such as cholesterol, to the membranes …

The double‐membrane‐bound autophagosome is formed by the closure of a structure
called the phagophore, origin of which is still unclear. The endoplasmic reticulum (ER) is …

Atherosclerosis is a multifactorial disease of the vasculature, and shear stress is a crucial
regulator of its process. Disturbed flow promotes atherosclerotic effects, while laminar flow …

Primary cilia are small, antenna-like organelles that detect and transduce chemical and
mechanical cues in the extracellular environment, regulating cell behavior and, in turn …

Shear stress generated by urinary fluid flow is an important regulator of renal function. Its
dysregulation is observed in various chronic and acute kidney diseases. Previously, we …