Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

[HTML][HTML] Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics

BD Paul, SH Snyder, K Kashfi - Redox biology, 2021 - Elsevier
Hydrogen sulfide (H 2 S) was once considered to have only toxic properties, until it was
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

[HTML][HTML] Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies

H Lin, Y Yu, L Zhu, N Lai, L Zhang, Y Guo, X Lin… - Redox Biology, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

Environmental toxicology of hydrogen sulfide

SLM Rubright, LL Pearce, J Peterson - Nitric Oxide, 2017 - Elsevier
The passenger-carrying paddle steamer Princess Alice was sunk in a collision on the River
Thames in 1878 with the loss of over 640 lives and, curiously, may represent one of the …

The mitochondrial coenzyme Q junction and complex III: Biochemistry and pathophysiology

R Banerjee, J Purhonen, J Kallijärvi - The FEBS journal, 2022 - Wiley Online Library
Coenzyme Q (CoQ, ubiquinone) is the electron‐carrying lipid in the mitochondrial electron
transport system (ETS). In mammals, it serves as the electron acceptor for nine mitochondrial …

Hydrogen sulfide biochemistry and interplay with other gaseous mediators in mammalian physiology

A Giuffrè, JB Vicente - Oxidative medicine and cellular longevity, 2018 - Wiley Online Library
Hydrogen sulfide (H2S) has emerged as a relevant signaling molecule in physiology, taking
its seat as a bona fide gasotransmitter akin to nitric oxide (NO) and carbon monoxide (CO) …

Hydrogen sulfide biology and its role in cancer

S Khattak, MA Rauf, NH Khan, QQ Zhang, HJ Chen… - Molecules, 2022 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

A Katsouda, SI Bibli, A Pyriochou, C Szabo… - Pharmacological …, 2016 - Elsevier
Recent studies have implicated endogenously produced H 2 S in the angiogenic process.
On one hand, pharmacological inhibition and silencing of the enzymes involved in H 2 S …

[HTML][HTML] Nanomotor-based H2S donor with mitochondrial targeting function for treatment of Parkinson's disease

Z Zhao, L Chen, C Yang, W Guo, Y Huang, W Wang… - Bioactive Materials, 2024 - Elsevier
Reduction of endogenous hydrogen sulfide (H 2 S) is considered to have an important
impact on the progress of Parkinson's disease (PD), thus exogenous H 2 S supplementation …