Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis

JL Bennett, AG Pratt, R Dodds, AA Sayer… - Nature Reviews …, 2023 - nature.com
Sarcopenia, a disorder that involves the generalized loss of skeletal muscle strength and
mass, was formally recognized as a disease by its inclusion in the International …

Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update

GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …

Inflammaging: The ground for sarcopenia?

Z Liang, T Zhang, H Liu, Z Li, L Peng, C Wang… - Experimental …, 2022 - Elsevier
Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …

The association between sarcopenia and diabetes: from pathophysiology mechanism to therapeutic strategy

H Chen, X Huang, M Dong, S Wen… - … Syndrome and Obesity, 2023 - Taylor & Francis
Diabetes and sarcopenia are emerging as serious public health issues. Sarcopenia, an age-
related disorder characterized by loss of skeletal muscle mass and function, is recognized …

Fiber-type shifting in sarcopenia of old age: proteomic profiling of the contractile apparatus of skeletal muscles

P Dowling, S Gargan, D Swandulla… - International Journal of …, 2023 - mdpi.com
The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men

A Granic, K Suetterlin, T Shavlakadze… - Clinical …, 2023 - portlandpress.com
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …

Understanding the consequences of fatty bone and fatty muscle: how the osteosarcopenic adiposity phenotype uncovers the deterioration of body composition

K Hu, E Deya Edelen, W Zhuo, A Khan, J Orbegoso… - Metabolites, 2023 - mdpi.com
Adiposity is central to aging and several chronic diseases. Adiposity encompasses not just
the excess adipose tissue but also body fat redistribution, fat infiltration, hypertrophy of …

A metabolic perspective of the neutrophil life cycle: new avenues in immunometabolism

MK Thind, HH Uhlig, M Glogauer, N Palaniyar… - Frontiers in …, 2024 - frontiersin.org
Neutrophils are the most abundant innate immune cells. Multiple mechanisms allow them to
engage a wide range of metabolic pathways for biosynthesis and bioenergetics for …

Resistin as a systemic inflammation-related biomarker for sarcopenia in patients with chronic obstructive pulmonary disease

J Gao, M Deng, Y Li, Y Yin, X Zhou, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Sarcopenia is common in patients with chronic obstructive pulmonary disease
(COPD) and is mainly caused by systemic inflammation. Resistin acts as a proinflammatory …

Differentially expressed genes and molecular susceptibility to human age-related diseases

S Shikhevich, I Chadaeva, B Khandaev… - International Journal of …, 2023 - mdpi.com
Mainstream transcriptome profiling of susceptibility versus resistance to age-related
diseases (ARDs) is focused on differentially expressed genes (DEGs) specific to gender …